摘要
目的探讨初产妇产褥期感染的病原学特点及其危险因素,为临床诊疗提供参考。方法收集2016年7月1日~2019年12月31日在中一东北国际医院分娩的1123例初产妇的临床资料,其中发生产褥期感染47例,感染率为4.18%,通过临床微生物学检验分析病原学特点,并对产褥期感染危险因素进行单因素与多因素Logistic分析。结果47例产褥期感染产妇共培养出51株菌株,革兰氏阴性菌占54.90%,其中大肠埃希菌占27.45%,占比略高;革兰氏阳性菌占45.10%,以金黄色葡萄球菌为主,占19.61%。胎膜早破、产后出血、合并阴道炎以及妊娠期糖尿病/高血压的初产妇发生产褥期感染的概率明显增加,差异有统计学意义(P<0.05);产程、年龄、生产方式、贫血、合并慢性病产妇的感染率比较差异无统计学意义(P>0.05)。胎膜早破、合并阴道炎、产后出血以及妊娠期糖尿病/高血压为初产妇产褥期感染的危险因素(P<0.05)。结论初产妇发生产褥期感染的危险因素可归纳为胎膜早破、合并阴道炎、产后出血以及妊娠期糖尿病/高血压,病原学分析显示感染菌株以革兰氏阴性菌较为常见。
Objective To explore the etiological characteristics and risk factors of puerperal infection in primipara,and to provide reference for clinical diagnosis and treatment.Methods The clinical data of a total of 1123 primiparas who delivered in the Zhongyi Northeast International Hospital from July 1,2016 to December 31,2019 were collected.Among them,47 cases had puerperal infection,and the infection rate was 4.18%.The etiological characteristics were analyzed by clinical microbiology test,and the risk factors of puerperal infection were analyzed by univariate and multivariate Logistic analysis.Results A total of 51 strains were isolated from 47 puerperal women with puerperal infection,of which 54.90%were Gram-negative bacteria,27.45%were Escherichia coli,accounted for slightly higher proportion;45.10%of Gram-positive bacteria were mainly Staphylococcus aureus,accounted for 19.61%.The incidence of puerperal infection in primipara with premature rupture of membranes,postpartum hemorrhage,vaginitis and gestational diabetes/hypertension was significantly increased,the differences were statistically significant(P<0.05).There was no significant difference in the infection rate of primipara with stage of labor,age,mode of production,anemia,and chronic diseases(P>0.05).Premature rupture of membranes,vaginitis,postpartum hemorrhage and gestational diabetes/hypertension were risk factors of puerperal infection in primipara(P<0.05).Conclusion The risk factors of puerperal infection in primipara can be summarized as premature rupture of membranes,vaginitis,postpartum hemorrhage and gestational diabetes/hypertension.Etiological analysis showed that Gram negative bacteria are the most common pathogens.
作者
曲子璎
QU Zi-ying(Department of Obstetrics,Zhongyi Northeast International Hospital Co.,Ltd.,Liaoning Province,Shenyang110000,China)
出处
《中国当代医药》
CAS
2021年第6期100-102,共3页
China Modern Medicine
关键词
产褥期感染
初产妇
病原学特点
危险因素
Puerperal infection
Primipara
Etiological characteristics
Risk factors
