摘要
目的总结姜惠中教授诊疗多囊卵巢综合征(Polycystic ovary syndrome,PCOS)的学术思想及辨治规律。方法采用古今云医案平台数据挖掘系统中关联规则及层次聚类方法分析姜惠中教授2017年11月-2019年11月治疗的PCOS医案,总结归纳其学术思想及辨治规律。结果纳入病案162例,共381诊次。涉及中医疾病11种、证型12种、症状144个。证型拆分得到4个实性证素(气滞、痰湿、血瘀、火热)、3个虚性证素(阳虚、阴虚、气虚)及3个病位证素(肝、肾、脾)。高频症状分层聚类后得到肾虚肝郁证、肝肾阴虚证、肾虚血瘀证、肝郁痰阻证4个证型的核心症状组合。共有处方381张,涉及150味中药,首见甘温类、肝经药,高频药物关联规则得到药对14对、角药6对。通过对高频药物分层聚类得到6类核心药物组合,分别体现了滋补肝肾、温补肾阳、补肾疏肝、行气化瘀、化痰利湿的治法。结论姜教授治疗PCOS注重辨病与辨证结合,认为PCOS核心病机为肾虚肝郁,治疗以补肾疏肝为主,辅以健脾、祛痰、化瘀。
Objective To summarize Professor Jiang Huizhong’s academic thoughts and rules of differentiation in the treatment of polycystic ovary syndrome(PCOS). Methods The PCOS cases treated by Professor Jiang from November2017 to November 2019 were analyzed by using data mining on the cloud platform of ancient and modern medical records. Results A total of 162 cases were included with 381 consultations, involving 11 kinds of TCM diseases,12 types of syndromes, and 144 symptoms. The 4 main syndromes were kidney deficiency and liver depression syndrome,liver and kidney yin deficiency syndrome, kidney deficiency blood stasis syndrome, liver depression and phlegm obstruction syndrome. The syndromes were further analyzed, producing 4 excess syndromes(qi stagnation, phlegm dampness, blood stasis, fiery), 3 deficiency syndromes(yang deficiency, yin deficiency, qi deficiency) and 3 disease sites(liver, kidney, spleen). A total of 381 prescriptions were collected, involving 150 medicinals mainly in the sweet and warm natured class and liver meridian class. The association rules of high-frequency medicinals showed 14 sets of couplet medicinals and 6 sets of tripartite medicinals. By stratifying clustering of high-frequency medicinals, 6 types of core medicinal combinations were obtained, which respectively embodies the treatment methods of nourishing the liver and kidney, warming the kidney yang, nourishing the kidney and relieving the liver, activating qi and resolving stasis,dissipating phlegm and dampness. Conclusion Professor Jiang Huizhong pays attention to the differentiation of disease and syndrome in the treatment of PCOS and believes that the core pathogenesis of PCOS is kidney deficiency and liver stagnation. Thus, the treatment should mainly focus on nourishing the kidney and liver, supplemented by strengthening the spleen, dissipating the phlegm, and resolving the stasis.
作者
熊梦欣
向楠
周亚娜
邓阿黎
詹妮
朱英华
王凯宁
蔡生兴
张慧丰
赵玉凤
Xiong Mengxin;Xiang Nan;Zhou Yana;Deng Ali;Zhan Ni;Zhu Yinghua(Hubei University of Chinese Medicine Clinical College of TCM,Wuhan 430061,China;Hubei University of Chinese Medicine First Clinical College,Wuhan 430061,China;Hubei Provincial Hospital of TCM Obstetrics and Gynecology,Wuhan 430074,China;Hubei Provincial Hospital of TCM Oncology,Wuhan 430074,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2020年第11期4001-4008,共8页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
湖北省卫生健康委员会中医药科研项目(ZY2019M001):姜惠中治疗多囊卵巢综合征临床经验传承的研究
负责人:邓阿黎
湖北省高等学校优秀中青年科技创新团队项目(T201708):中医药临床疗效评价
负责人:邓阿黎。
关键词
多囊卵巢综合征
数据挖掘
名医经验
姜惠中
Polycystic ovary syndrome
Data mining
Famous doctors experience
Jiang Huizhong
