摘要
目的分析儿童新型冠状病毒肺炎(简称新冠肺炎)疑似病例的流行病学及临床特点。方法选取2020年1月23日—2月23日湖南省儿童医院感染科隔离留观病房的46例新冠肺炎疑似病例进行回顾性分析。结果疑似病例流行病学史:有湖北旅居史的33例(71.8%),所在社区有确诊病例的7例(15.2%),接触高度疑似病例的2例(4%),当地新型冠状病毒核酸检测可疑阳性的2例(4%),聚集性发病的2例(4%),均无确诊病人直接接触史;临床表现为发热或/和咳嗽;血常规、C反应蛋白、降钙素原正常,肝肾功能均正常;流感病毒、呼吸道合胞病毒、支原体检出率分别为19.6%、10.9%、15.2%;胸片无特异性表现;所有疑似病例新型冠状病毒核酸检测均阴性;经治疗后基本痊愈出院,2周后随访均正常。结论儿童疑似病例流行病学史以湖北旅居史为主,临床表现以发热多见,需注意排查流感病毒、呼吸道合胞病毒、支原体等常见病原体;疑似病例确诊率低,核酸检测仍是最主要的病原学确诊方法。
Objective To analyze the epidemiological and clinical characteristics of suspected cases of COVID-19 in children. Methods We retrospectively analyzed 46 suspected COVID-19 cases from the isolation wards of Infection Department, Hunan Children’s Hospital from January 23 to February 23, 2020. Results The epidemiological history of the suspected cases displayed that there were 33(71.8%) cases having a history of travelling or living in Hubei Province, 7(15.2%) cases from communities with confirmed cases, 2(4%) cases contacting with highly suspected cases, 2(4%) cases with local detection results of SARS-CoV-2 nucleic acid suspected positive and 2(4%) cases with aggregated incidence, and all the cases had no history of direct contact with diagnosed patients. Clinical manifestations were fever or/and cough. Blood routine, C reactive protein, procalcitonin, and liver and renal functions were normal. The detection rates of influenza virus, respiratory syncytial virus and mycoplasma were 19.6%, 10.9% and 15.2%, respectively. Chest radiographs showed no specificity. All the results of SARS-CoV-2 nucleic acid tests of the suspected cases were negative. All the patients were recovered and discharged after treatment, and the follow-ups after two weeks showed all normal. Conclusions The epidemiological history of the suspected cases in children was mainly the history of travelling or living in Hubei Province, and fever was the main clinical manifestation. It is necessary to detect common pathogens such as influenza virus, respiratory syncytial virus and mycoplasma. The confirmed diagnosis rate of the suspected cases is low. Nucleic acid detection is still the main etiological diagnosis method.
作者
肖耿吉
罗如平
胡敏
李逊
谭李红
XIAO Geng-ji;LUO Ru-ping;HU Min;LI Xun;TAN Li-hong(Hunan Children's Hospital,Changsha,Hunan 410007,China;Second Xiangya Hospital of Central South University,Changsha,Hunan 410007,China)
出处
《实用预防医学》
CAS
2021年第3期272-274,共3页
Practical Preventive Medicine
