摘要
目的分析探讨枣仁安神胶囊治疗心血亏虚型艾滋病失眠患者的临床疗效。方法将我院接受含依非韦伦抗病毒方案,辩证分型为心血亏虚型艾滋病失眠患者随机分成两组,每组42例。观察组予枣仁安神胶囊干预治疗,对照组予艾司唑仑片治疗,疗程8周,观察两组睡眠质量改善情况。结果观察组总有效率80.9%,对照组总有效率83.3%,两组比较差异无统计学意义(P>0.05),两组患者治疗后的PSQI总分、ISI及中医症状分级量化标准表总分均低于治疗前,各组前后比较差异有统计学意义(P<0.05);观察组患者治疗后ISI与中医症状分级量化标准表总分低于对照组,组间比较差异有统计学意义(P<0.05);观察组不良反应总发生率4.8%,对照组26.2%,两组比较差异有统计学意义(P<0.05)。结论枣仁安神胶囊对含依非韦伦方案心血亏虚型艾滋病失眠症患者具有一定疗效,且不良反应少,值得临床推荐应用。
OBJECTIVE Analysis of ZaoRen AnShen capsule in the treatment of heart blood deficiency type AIDS insomniai.METHODS According to the antiviral program of enfeveren,the patients were divided into two groups randomly,42 cases in each group.The observation group was treated with ZaoRen AnShen capsule,while the control group was treated with estazolam tablets for 8 weeks,and the improvement of sleep quality was observed in the two groups.RESULTS The total effective rate was 80.9%in the observation group and 83.3%in the control group.There was no significant difference between the two groups(P>0.05).After treatment,the total score of PSQI,ISI and the total score of TCM symptom classification and quantification standard table were lower than before treatment,and the difference between the two groups was statistically significant(P<0.05);After treatment,the total score of ISI and TCM symptom grading and quantification standard table in the observation group was lower than that in the control group,and the difference between the two groups was statistically significant(P<0.05);The total incidence of adverse reactions was 4.8%in the observation group and 26.2%in the control group(P<0.05).CONCLUSION ZaoRen AnShen capsule has a certain effect on the insomnia patients with heart blood deficiency type of AIDS with yifeiweilun scheme,and has few adverse reactions,which is worth clinical recommendation.
作者
吉婧
欧松
阳辉
邓晓军
杨炼
周玉红
JI Jing;OU Song;YANG Hui;DENG Xiao-jun;YANG Lian;ZHOU Yu-hong(The Third People′s Hospital of Hengyang City,Hengyang 421005,China)
出处
《海峡药学》
2021年第2期111-113,共3页
Strait Pharmaceutical Journal
基金
湖南省中医药治疗艾滋病项目,湘中医药函〔2019〕96号。
关键词
枣仁安神胶囊
心血亏虚型
艾滋病
失眠
ZaoRen AnShen capsule
Deficiency of heart and blood
HIV/AIDS
Insomnia
