摘要
目的了解北京市孕妇血清维生素D水平状况,并探讨其与某些妊娠并发症的相关性。方法回顾性选取2017年1月至2019年8月在北京妇产医院进行了维生素D检测的单胎孕妇3888例,将其分为无任何妊娠并发症的健康孕妇和患有妊娠并发症的孕妇两组,并分别进一步分组进行统计分析。结果妊娠期妇女维生素D缺乏的现象普遍存在,健康孕妇当中,维生素D不足率和缺乏率分别为30.54%和25.88%,且随着孕期的增加,孕妇血清维生素D水平逐步升高。与对照组相比,妊娠糖尿病组维生素D水平及缺乏率差异无统计学意义(P>0.05),先兆流产组维生素D水平明显偏低(P<0.05),先兆早产组维生素D水平明显偏低(P<0.05),缺乏率明显偏高(P<0.05)。结论本地区孕妇维生素D水平的现状不容乐观,且维生素D缺乏可能与先兆流产和先兆早产密切相关。
Objective To investigate the level of vitamin D in pregnant women in Beijing area and its correlation with multiple pregnancy complications.Methods 3888 singleton pregnant women who underwent vitamin D test in Beijing Obstetrics and Gynecology Hospital from January,2017 to August,2019 were retrospectively selected and divided into two groups:healthy pregnant women without any pregnancy complications and pregnant women with pregnancy complications.Then further statistical analysis was carried out in these subjects.Results Vitamin D deficiency in pregnant women was shown to be common.The lack and deficiency of vitamin D accounted for 30.54%and 25.88%in healthy pregnant women,respectively.The serum vitamin D level in pregnant women increased with gestational age.On the other hand,compared with the control group,no significant difference in vitamin D level and deficiency rate in the gestational diabetes mellitus group was found(P>0.05)and the vitamin D content in the threatened abortion group was significantly lower(P<0.05)and the vitamin D content was significantly lower(P<0.05),while the deficiency rate was significantly higher in the threatened premature birth group(P<0.05).Conclusion Our study indicates that the present situation of vitamin D content in pregnant women in Beijing area is not optimistic,and vitamin D deficiency may be closely related to threatened abortion and threatened premature delivery.
作者
肖征
贾妍
曹正
翟燕红
战思恩
XIAO Zheng;JIA Yan;CAO Zheng;ZHAI Yanhong;ZHAN Sien(Department of Laboratory Medicine,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing 100026,China)
出处
《标记免疫分析与临床》
CAS
2021年第2期194-196,209,共4页
Labeled Immunoassays and Clinical Medicine
基金
首都医科大学附属北京妇产医院中青年学科骨干培养专项(编号:FCYY201708)。
关键词
维生素D
妊娠糖尿病
先兆流产
先兆早产
Vitamin D
Gestational diabetes mellitus
Threatened abortion
Threatened premature delivery
