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甲状腺次全切术治疗双侧结节性甲状腺肿的疗效 被引量:2

Efficacy of Subtotal Thyroidectomy for Bilateral Nodular Goiter
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摘要 目的研究双侧结节性甲状腺肿(nodular goiter,NG)患者行甲状腺全切术、甲状腺次全切术的治疗效果。方法样本采集2014年1月—2020年3月本院收治的100例双侧NG患者,随机分对照组(甲状腺全切术)与观察组(甲状腺次全切术)各50例,比较两组手术效果、甲状腺功能指标及并发症发生情况。结果两组术中出血量比较差异无统计学意义(P> 0.05);与对照组比较,观察组手术、住院时间较短,镇静剂使用量较少,游离三碘甲状腺原氨酸(free triiodothyronine,FT3)、游离甲状腺素(free thyroxine,FT4)、促甲状腺激素(thyroid stimulating hormone,TSH)水平较低,差异均有统计学意义(P <0.05);观察组手术总有效率(98.00%)高于对照组(84.00%),并发症发生率(4.00%)低于对照组(18.00%),比较差异均有统计学意义(P <0.05)。结论与甲状腺全切术比较,甲状腺次全切术治疗双侧NG患者能改善甲状腺功能、提高整体疗效。 Objective To study the effect of total thyroidectomy and subtotal thyroidectomy in patients with bilateral nodular goiter(NG).Methods Samples were collected from 100 patients with bilateral NG admitted to our hospital from January 2014 to March 2020,randomly divided into control group(total thyroidectomy)and observation group(subtotal thyroidectomy),each with 50 cases,and the two groups were compared of surgical effects,thyroid function indicators and complications.Results There was no significant difference in the amount of intraoperative blood loss between the two groups(P>0.05).Compared with the control group,the observation group had shorter operating time and hospital stays,less sedatives,the levels of free triiodothyronine(FT3),free thyroxine(FT4)and thyroid stimulating hormone(TSH)were low,and the differences were statistically significant(P<0.05);the total effective rate of surgery in the observation group(98.00%)was higher than that in the control group(84.00%),the complication rate(4.00%)was lower than that in the control group(18.00%),and the differences were statistically significant(P<0.05).Conclusion Compared with total thyroidectomy,subtotal thyroidectomy for bilateral NG patients can improve thyroid function and improve overall efficacy.
作者 陈锐 CHEN Rui(First Department of Surgery,Jian'ou Municipal Hospital,Fujian Province,Jian'ou Fujian 353100,China)
出处 《中国卫生标准管理》 2021年第4期73-76,共4页 China Health Standard Management
关键词 双侧结节性甲状腺肿 甲状腺全切术 甲状腺次全切术 并发症 手术时间 住院时间 bilateral nodular goiter total thyroidectomy subtotal thyroidectomy complications operating time hospital stay
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