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肺结核并发噬血细胞综合征一例 被引量:1

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摘要 噬血细胞综合征(hemophagocytic syndrome,HPS)是一组由原发或继发因素导致免疫系统异常激活而引发的多器官过度炎性反应的临床综合征,组织学特征为组织细胞/巨噬细胞过度增生和活化。常见症状主要为持续高热、全血细胞减少、肝脾进行性肿大、明显出血及贫血、感染,以及一些铁蛋白升高,肝功能异常等[1]。病情进展凶险,病死率非常高[2-3]。其中,EB病毒是其最常见的继发病因,而继发于结核病的报道较为少见。
出处 《中国防痨杂志》 CAS CSCD 2020年第12期1352-1353,共2页 Chinese Journal of Antituberculosis
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  • 1Henter JI, Aric5 M, Egeler RM, et al. HLH-94 : a treatment pmtol for hemophagocytic lymphohistiocytosis. HLA study Group of the Histiocytel Society. Med Pediat Oncol, 1997 ; 28 (5) :342 - 347.
  • 2Henter JI, Home A, Arico M, et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer,2007 ; 48(2) :124 - 131.
  • 3Henter JI, Samuelsson-Horne A, Aricb M, et al. Treatment of hemophagoeytic lymphohistioeytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood, 2002 ; 100 ( 7 ) :2367 - 2373.
  • 4Ishii E, Ohga S, Tanimura M, et al. Clinical and epidemiologic studies of familial haemophagocytic lymphohistiocytosis in Japan. Japan LCH Study Group. Med Pediatr Oncol, 1998 (5); 30:276 - 283.
  • 5Ohadi M, Lalloz MR, Sham P, et al. Localization of a gene for familial hemophagocytic lymphohistiocytosis at chromosome 9q21.3-22 by homozygosity mapping. Am J Hum Genet, 1999; 64( 1 ) : 165 - 171.
  • 6Dufourcq-Lagelouse R, Jabado N, Le Deist F, et al. Linkage of familial hemophagocytic lymphohistocytosis to 10q21-22 and evidence for heterogeneity. Am J Hum Genet,1999 ; 64( 1 ) :172 - 179.
  • 7Stepp SE, Dufourcq-Lagelouse R, Le Deist F, et al. Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Sience, 1999 ; 286(5446) : 1957 - 1959.
  • 8Feldmann J, Callebaut I, Raposo G, et al. Munc 13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis ( FHL3 ). Cell, 2003 ; 115 ( 4 ) :461 - 473.
  • 9zur Stadt U, Schmidt S, Kasper B, et al. Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11. Hum Mol Genet, 2005 ; 14(6) :827 -834.
  • 10Ishii E, Ueda I, Shirakawa R, et al. Genetic subtypes of familial hemophagocytic lymphohistiocytosis: correlations with clinical features and cytotoxic T lymphocyte/natural killer cell functions. Blood, 2005 ; 105 (9) :3442 - 3448.

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