摘要
随着免疫功能缺陷人群数量的增加,脊柱真菌感染发病率随之升高,其流行病学特征、诊断及治疗受到越来越多的关注。真菌感染侵犯脊柱较罕见,易出现诊断延迟,漏诊及误诊率高,患者存在死亡风险。目前的检测手段缺乏特异性,造成确诊困难,真菌种类的鉴别很难通过微生物培养实现。非手术治疗仍是脊柱真菌感染的主要治疗手段,但真菌对抗菌药物存在耐药性,复发率较高,故是否选择非手术治疗仍然存在争议。本文就脊柱真菌感染的研究进展作相关综述,为其临床诊断和治疗提供一定参考。
With the increasing number of immunocompromised patients,the incidence of fungal vetebral osteomyelitis was higher.The epidemiology,diagnosis and treatment of this disease received growing attention.Fungal osteomyelitis was a rare disease,with high rates of misdiagnosis,missed diagnosis and delayed diagnosis,which is closely related to the risk of death.However,the specificity of culture currently is very difficult to identify fungal species.Non-operative measures remain the primary curative modality,which is still controversial because of drug resistance and high frequency of recurrence.The research progress of spinal fungal infection was reviewed and some references for clinical diagnosis and treatment were provided in this article.
作者
徐仲阳
吕超亮
卢公标
陆继收
Xu Zhongyang;Lv Chaoliang;Lu Gongbiao;Lu Jishou(Department of Spine Surgery,Jining First People’s Hospital,Jining 272011,China)
出处
《中华实验和临床感染病杂志（电子版）》
CAS
2021年第1期11-14,共4页
Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)
基金
济宁市第一人民医院博士基金(No.2019002)
山东省医药卫生科技发展计划(No.2014WS0276)。
关键词
脊柱
真菌
感染
Spine
Fungus
Infection
