摘要
目的评价小儿肺炎支原体肺炎患儿在序贯治疗中应用红霉素联合阿奇霉素的临床效果。方法选取我院2017年1月至2019年12月收治入院的小儿肺炎支原体肺炎患儿110例为研究对象,采用计算机进行随机分组,参照组(n=55)、试验组(n=55)。在常规治疗基础上,参照组增添红霉素参与治疗,试验组则选择红霉素联合阿奇霉素参与治疗。对比分析治疗效果。结果试验组总有效率与参照组对比更高(P<0.05);试验组住院时间、退热时间、啰音消失时间、咳嗽消失时间与参照组对比均更短(P<0.05);经治疗后,两组患儿血清C反应蛋白(CRP)和血清淀粉样蛋白A(SAA)水平均有所下降,且试验组低于参照组(P<0.05);试验组不良反应发生率与参照组对比更低(P<0.05)。结论应用红霉素联合阿奇霉素序贯治疗肺炎支原体肺炎患儿临床效果显著。
Objective To evaluate the clinical effect of erythromycin combined with azithromycin in sequential treatment of children with mycoplasma pneumoniae pneumonia.Methods One hundred and ten children with mycoplasma pneumoniae pneumonia in our hospital(admitted between January 2017 and December 2019)were included in the study,randomized by computer,and divided into:reference group(n=55),experimental group(n=55).On the basis of conventional treatment,erythromycin was applied to the reference group,and erythromycin combined with azithromycin was selected for the experimental group.Comparative analysis of treatment effects.Results The total effective rate of the experimental group was higher than that of the reference group(P<0.05);the hospitalization time,the time of fever,the time of rale disappearance,the time of cough disappearance in the experimental group were shorter than that of the reference group(P<0.05).After treatment,the levels of serum C-reactive protein(CRP)and serum amyloid A(SAA)in the two groups were decreased,and the experimental group was lower than the reference group(P<0.05).The incidence of adverse reactions in the experimental group was lower than that of the reference group(P<0.05).Conclusion The application of erythromycin combined with azithromycin in the treatment of children with mycoplasma pneumoniae pneumonia has a significant clinical effect.
作者
张福添
杨仁贵
ZHANG Futian;YANG Ren'gui(Department of Pediatrics,Maternal and Child Health Hospital of Xianyou County,Xianyou 351200,China)
出处
《中国医药指南》
2021年第6期4-6,共3页
Guide of China Medicine
关键词
肺炎支原体肺炎
序贯治疗
阿奇霉素
不良反应
红霉素
Mycoplasma pneumoniae pneumonia
Sequential treatment
Azithromycin
Adverse reactions
Erythromycin
