摘要
目的比较乳腺癌保乳术后常规放疗与调强放疗的相关参数。方法选取我院46例乳腺癌保乳术患者,按入院顺序将其分为对照组与观察组,分别在术后实施常规放疗计划(CRT)与三维适形调强放疗计划(IMRT)。比较两组患者的靶区均匀性(用"PTV剂量体积比"表示)以及正常组织受照量(用"肺脏、心脏照射剂量体积比"表示)的差异。结果观察组V95、V107、V110与V115时的PTV剂量体积比,V10、V20、V30、V40时的肺脏照射剂量体积比,以及左侧乳腺癌患者V5与V30时的心脏照射剂量体积比,相比于对照组均明显降低,数据差异显著(均P<0.05)。结论相比于常规化疗,对乳腺癌保乳术患者展开术后调强放疗,可优化计划靶区分布,靶区均匀性更高,肺脏及心脏的受照量更低。
Objective To observe and compare the parameters of conventional radiotherapy and intensity-modulated radiotherapy after breast-conserving surgery for breast cancer.Methods Forty-six patients with breast cancer conserving surgery in our hospital were selected and divided into control group and observation group according to the order of admission.Routine radiotherapy plan(CRT)and three-dimensional conformal intense-modulated radiotherapy plan(IMRT)were respectively carried out after surgery.The differences in target uniformity(PTV dose to volume ratio)and normal tissue exposure(lung to heart dose to volume ratio)were compared between the two groups.Results The PTV dose-volume ratios of V95,V107,V110 and V115 in the observation group,the lung irradiation dose-volume ratios of V10,V20,V30 and V40,and the heart irradiation dose-volume ratios of V5 and V30 in the left breast cancer patients were significantly lower than those in the control group,the differences were significant(all P<0.05).Conclusion Compared with conventional chemotherapy,intensery-modulated radiotherapy(IMRT)for breast cancer patients undergoing breast conserving surgery can optimize the distribution of planned target areas with higher target uniformity and lower exposure to lung and heart.
作者
滕静
TENG Jing(Central Hospital of Yingkou Economic and Technological Development Zone(The Sixth People's Hospital of Yingkou),Yingkou 115007,China)
出处
《中国医药指南》
2021年第6期83-84,共2页
Guide of China Medicine
关键词
乳腺癌保乳术
调强放疗
常规放疗
参数比较
Breast cancer breast conserving surgery
Intensity modulated radiotherapy
Conventional radiotherapy
Parameter to compare
