摘要
目的评价分析地特胰岛素联合门冬胰岛素治疗妊娠合并糖尿病患者的安全性及有效性。方法选取2017年3月至2019年11月于本院待产的妊娠合并糖尿病患者80例为研究对象,按照入院顺序分为两组,各40例。对照组使用生物合成人胰岛素进行治疗,研究组使用地特胰岛素联合门冬胰岛素进行治疗,比较两组患者的血糖水平、母婴分娩结果、血糖达标率、低血糖以及严重低血糖发生率、血糖达标时间。结果研究组FBG、2 h PG、HbAlc均低于对照组(P<0.05);研究组早产、妊高症发生率低于对照组,但差异无统计学意义;研究组剖宫产、巨大儿、产褥感染发生率明显低于对照组(P<0.05);研究组血糖达标率高于对照组,低血糖及严重低血糖发生率均低于对照组,血糖达标时间短于对照组(P<0.05)。结论使用地特胰岛素联合门冬胰岛素治疗妊娠合并糖尿病患者,能有效降低并稳定患者的血糖水平,减少母婴不良分娩结局,提高患者的血糖达标率,降低患者低血糖以及严重低血糖发生率,缩短患者的血糖达标时间,具有较高的临床应用价值,值得推广使用。
Objective To evaluate the safety and efficacy of insulin diltiazem combined with insulin aspart in the treatment of gestational diabetes mellitus. Methods 80 pregnant women with diabetes mellitus were selected from March 2017 to November 2019 in our hospital. According to the order of admission, they were divided into two groups, with 40 cases in each group. The control group was treated with biosynthesized human insulin, the study group was treated with dieterian combined with asparagine, and the blood glucose results of delivery. Blood glucose standard rate, hypoglycemia and serious hypoglycemia, blood glucose standard time were compared between the two groups. Results The FBG, 2 h PG and HbAlc in the study group were all lower than those in the control group(P<0.05). Preterm birth and pregnancy induced hypertension in the study group were lower than those in the control group, but the difference was not statistically significant. The incidence of cesarean section, macrosomia and puerperal infection in the study group were significantly lower than that in the control group(P<0.05). The blood glucose compliance rate of the study group was higher than that of the control group, the incidence of hypoglycemia and severe hypoglycemia were lower than that of the control group,and the blood glucose compliance time was shorter than that of the control group(P<0.05). Conclusion The treatment of gestational patients with diabetes mellitus by using insulin diltiazem combined with aspart insulin can effectively reduce and stabilize the blood glucose level of the patients,reduce the incidence of poor delivery results of mothers and infants, improve the blood glucose standard rate of the patients, reduce the incidence of hypoglycemia and severe hypoglycemia, and shorten the blood glucose standard time of the patients. It can be widely used.
作者
刘烨秋
LIU Yeqiu(Department of Obstetrics and Gynecology,Macheng Hospital of Traditional Chinese Medicine,Huanggang,Hubei,431600,China)
出处
《当代医学》
2021年第10期32-34,共3页
Contemporary Medicine
关键词
地特胰岛素
门冬胰岛素
妊娠合并糖尿病
安全性
有效性
Insulin diltiazem
Insulin aspartate
Pregnancy with diabetes mellitus
Safety
Effectiveness
