摘要
目的探讨急性脑梗死患者加味四妙勇安汤治疗的有效性及对患者血清超敏C反应蛋白(hs-CRP)、纤维蛋白原(Fg)水平的影响。方法选择2018年6月至2020年6月进行治疗的急性脑梗死患者92例,随机将其分为对照组和观察组,每组各为46例。对照组给予常规西药治疗,观察组给予加味四妙勇安汤治疗。比较治疗后症状积分、神经功能缺损量表(NIHSS)、神经系统评分量表(NDS)和简易智力状态检查量表(MMSE)评分以及hs-CRP、白细胞介素(IL-6)、Fg水平情况。结果观察组治疗后神志状态、语言表达情况、上下肢活动情况以及综合能力分值高于对照组(P<0.05);治疗后观察组患者的NIHSS和NDS评分均低于对照组(P<0.05),MMSE评分高于对照组(P<0.05);治疗后hs-CRP、IL-6、Fg水平均显著低于对照组(P<0.05)。结论加味四妙勇安汤治疗急性脑梗死患者疗效好,有利于神经细胞的修复和再生,值得推广应用。
Objective To investigate the effectiveness of modified SimiaoYongan Decoction for patients with acute cerebral infarction and its effect on serum hs-CRP and Fg levels.Methods A total of 92 patients with acute cerebral infarction who were treated from June 2018 to June 2020 were selected and randomly divided into a control group and an observation group,46 casesin each.The control group was treated with conventional western medicine,and the observation group was treated with Modified SimiaoYongan Decoction.The symptom scores,NIHSS,NDS and MMSE scores,and hs-CRP,IL-6,and Fg levels were compared after treatment.Results After treatment,the scores of mental state,language expression,upper and lower limb activities and comprehensive ability of the observation group were higher than those of the control group(P<0.05);after treatment,the NIHSS and NDS scores of the observation group were lower than those of the control group(P<0.05),the MMSE score was higher than the control group(P<0.05);hs-CRP,IL-6,and Fg levels after treatment were significantly lower than the control group(P<0.05).Conclusion Modified SimiaoYongan Decoction has a better effect in the treatment of patients with acute cerebral infarction.It can effectively improve the patient′s symptom scores,reduce serum hs-CRP,IL-6,Fg levels,and NIHSS and NDS scores,which is beneficial to the repair and regenerationof nerve cells.It has obvious effects and is worthy of popularization and application.
作者
朱兆武
Zhu Zhaowu(Department of Brain Disease,Jiamusi Hospital of Traditional Chinese Medicine,Hei Longjiang 154002,China)
出处
《山西医药杂志》
CAS
2021年第6期914-917,共4页
Shanxi Medical Journal
