摘要
目的:探讨运用经络理论在甲状腺良性结节临床辨证论治中的规律.方法:检索1950—2020年在中国知网(CNKI)、万方数据知识服务平台、维普等数据库中关于中医药治疗甲状腺良性结节的文献,提取文献纳入的中药、取穴处方等数据,对高频药物归经、高频穴位、经络进行频次分析、关联分析及聚类分析,并对所涉及的经络进行网络可视化分析.结果:本研究共收集文献110篇,其中纳入文献的中药处方92首,穴位处方18首.涉及中药137味,其中使用频次大于5次的中药47味、穴位33个,共涉及14条经脉.药物归经频次最高的为足厥阴肝经;关联分析显示药物高频归经之间的关联度较好的为足厥阴肝经→手厥阴心包经;相关性较好的穴位有天柱、大杼、曲骨、内关.高频药物聚类可得到8种组合,核心取穴组合6个.结论:数据挖掘结果表明经络辨证论治甲状腺良性结节的经验如下:结合经络循行路线,遵循远部取穴及近部取穴相结合的原则,选取以“疏肝、化痰、化瘀”为主要功效的经络及穴位.
Objective:To explore the application of meridian theory in clinical differentiation and treatment of benign thyroid nodules.Methods:The literatures on the treatment of benign thyroid nodules by TCM in CNKI,WANFANG database and VIP database from 1950 to 2020 were searched.The Traditional Chinese Medicine(TCM)and acupoint prescriptions included in the literatures were extracted,and the frequency analysis,correlation analysis and cluster analysis were conducted on the meridian tropism,high frequency acupoint location and meridians,The network visualization analysis of the involved meridians was carried out.Results:A total of 110 literatures were included,including 92 prescriptions of traditional Chinese medicine and 18 prescriptions of acupoints.Number of 137 kinds of TCM were involved,47 of which and 33 acupoints were used more than 5 times,involving 14 meridians.The highest frequency of drug meridian tropism was the liver meridian of foot Jueyin.The correlation analysis showed that the liver meridian of foot Jueyin→pericardium meridian of hand Jueyin had a better correlation.The acupoints with good correlation were Tianzhu,Dazhu,Qugu and Neiguan.Eight combinations can be obtained by high-frequency drug clustering,and 6 core acupoint combinations can be obtained.Conclusion:In the treatment of benign thyroid nodules,the meridians and acupoints with the main efficacy of“soothing the liver,resolving phlegm and removing blood stasis”are selected according to the principle of combining the meridians circulation route and the combination of the distal acupoints and the proximal acupoints.
作者
林洪
丁源
陈丽春
王李子牛
曾慧妍
金宇
LIN Hong;DING Yuan;CHEN Lichun;WANG Liziniu;ZENG Huiyan;JIN Yu(Department of Integrated Chinese and Western Medicine,The Second People s Hospital of Shenzhen,Shenzhen 518035,China;The Clinical School of Acupuncture and Rehabilitation,Guangzhou University of Traditional Chinese Medicine,Guangzhou 510405,China;The Second Clinical School of Guangzhou University of Traditional Chinese Medicine,Guangzhou 510405,China;Department of Endocrinology,Guangdong Provincial Hospital of Traditional Chinese Medicine,The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510105,China)
出处
《暨南大学学报（自然科学与医学版）》
CAS
CSCD
北大核心
2021年第2期210-218,共9页
Journal of Jinan University(Natural Science & Medicine Edition)
基金
深圳医疗卫生三名工程(SZSM201612049)。
关键词
经络
辨证论治
甲状腺良性结节
数据挖掘
meridians
syndrome differentiation and treatment
benign thyroid nodules
data mining
