摘要
随着胸腔镜技术普遍应用于肺癌患者手术,人们对利多卡因在胸科手术临床应用、作用药理方面的研究也逐步深入,发现其不仅具有局部麻醉和抗室性心律失常作用,还具有术后镇痛、减轻应激反应、抗炎、肺保护、抗肺部肿瘤、抗癌药增敏和减少术后认知功能障碍(POCD)等作用。本综述阐明胸腔镜下肺癌切除术术中静脉输注利多卡因的优势,旨在优化胸腔镜肺癌患者全身麻醉术中管理和改善预后。
The clinical application and pharmacological researches of thoracic surgery have been advanced with the widespread application of thoracoscopic technology in patients with lung cancer.It is found that it not only has the effects of local anesthesia and ventricular arrhythmia prevention,but also plays roles in postoperative analgesia,relieving stress reactions,anti-inflammation,lungs protection,anti-tumor in lungs,enhancing the sensitivity to anti-cancer drugs,and decreasing postoperative cognitive impairment(POCD).This review elucidated the advantages of intravenous infusion of lidocaine during thoracoscopic lung cancer resection so as to optimize the management of patients with thoracoscopic lung cancer under general anesthesia and improve their prognosis.
作者
邢智
张转
孙建宏
XING Zhi;ZHANG Zhuan;SUN Jianhong(Department of Anesthesiology,Affiliated Hospital of Yangzhou University,Yangzhou,Jiangsu,225000)
出处
《实用临床医药杂志》
CAS
2021年第1期121-124,共4页
Journal of Clinical Medicine in Practice
基金
江苏省卫生健康委员会基金面上项目(H2018049)。
关键词
利多卡因
胸腔镜
肺癌手术
围术期
lidocaine
thoracoscope
lung cancer surgery
perioperative period
