摘要
目的分析胎膜早破孕妇阴道B族链球菌、支原体、衣原体感染与妊娠结局的关系。方法将2017年3月至2019年2月山西医科大学第一附属医院产科收治的236例胎膜早破孕妇纳入胎膜早破组,另随机抽取同期收治的270例无胎膜早破正常孕妇纳入对照组。胎膜早破组足月102例、未足月134例。比较各组B族链球菌、支原体、衣原体感染情况,并比较胎膜早破组上述病原菌感染对妊娠结局的影响。结果胎膜早破组B族链球菌、支原体及衣原体感染率均显著高于对照组(P<0.05);胎膜早破组未足月孕妇支原体感染率显著高于足月孕妇(P<0.05),足月与未足月孕妇B族链球菌感染与衣原体感染率差异无统计学意义(P>0.05)。胎膜早破组中,B族链球菌、衣原体感染阳性孕妇早产、新生儿窒息、产后出血、低体重儿及绒毛膜羊膜炎发生率均显著高于阴性孕妇(P<0.05),支原体感染阳性孕妇早产、新生儿窒息、低体重儿发生率均显著高于阴性孕妇(P<0.05)。结论孕妇B族链球菌、支原体及衣原体感染与胎膜早破的发生密切相关,而胎膜早破孕妇B族链球菌、支原体及衣原体感染均可增加不良妊娠结局风险。
Objective To explore the relationship between streptococcus B,mycoplasma and chlamydia infection and pregnancy outcome in pregnant women with PROM.Methods 236 pregnant women with PROM admitted to the Department of Obstetrics in the No.1 Hospital Affiliated to Shanxi Medical University from March 2017 to February 2019 were enrolled as PROM group,and 270 normal pregnant women without PROM during the same period were randomly selected as the control group.In the PROM group,102 cases were full term and 134 cases non-full term.The infection of streptococcus B,mycoplasma and chlamydia in each group was compared,and the influence of the above pathogen infection on pregnancy outcome was compared in the PROM group.Results The infection rates of streptococcus B,mycoplasma and chlamydia in PROM group were significantly higher than those of the control group(P<0.05).The infection rate of mycoplasma in non-full term cases was significantly higher than that in full term pregnant cases(P<0.05),and there was no significant difference in the infection rate of streptococcus B and chlamydia between full-term cases and non-full-term cases(P>0.05).In PROM group,the incidence of premature delivery,neonatal asphyxia,postpartum hemorrhage,low birth weight were significantly higher than negative incidence of chorioamnionitis pregnant women(P<0.05),mycoplasma infection positive women preterm birth,neonatal asphyxia,the incidence of low birth weight in streptococcus B and chlamydia positive cases were significantly higher than in negative cases(P<0.05).Conclusions The infection of streptococcus B,mycoplasma and chlamydia in pregnant women is closely related to the occurrence of PROM,while the infection of streptococcus B,mycoplasma and chlamydia in pregnant women with PROM can increase the risk of adverse pregnancy outcome.
作者
姚婕
张延丽
YAO Jie;ZHANG Yanli(Department of Obstetrics,the No.1 Hospital Affiliated to Shanxi Medical University,Taiyuan 030000,Shanxi,China)
出处
《中国性科学》
2021年第1期72-75,共4页
Chinese Journal of Human Sexuality