摘要
目的探讨冥想干预对残留型精神分裂症患者认知功能的疗效观察。方法选取2019年1月—4月在上海市民政第一精神卫生中心长期住院治疗的残留型精神分裂症患者60例,采用随机数字表法将患者分为对照组和冥想组,对照组(n=30)采用常规治疗,冥想组(n=30)在常规治疗的基础上给予为期8个月的冥想干预。分别于入组前及治疗后8个月末采用重复性成套神经心理状态测验量表(RBANS)评定认知功能、简明精神病评定量表(BPRS)评定精神病性症状。结果干预后,冥想组即刻记忆及RBANS量表总分均高于干预前,且冥想组RBANS量表总分及即刻记忆、视觉广度、言语功能、注意力评分高于对照组,差异有统计学意义(P<0.05)。干预后,冥想组BPRS量表总分及焦虑抑郁、缺乏活力、激活性、敌对猜疑评分低于干预前,且冥想组BPRS量表总分及焦虑抑郁、缺乏活力、激活性评分低于对照组,差异有统计学意义(P<0.05)。结论残留型精神分裂症患者在常规治疗的基础上进行冥想干预,可改善认知功能缺损和精神病性症状,促进康复。
Objective To explore the curative effect of meditation intervention on cognitive function in patients with residual schizophrenia.Methods From January to April 2019,sixty patients with residual schizophrenia were recruited from Shanghai No.1 Civil Administration Mental Health Center who had been hospitalized in for a long time.The patients were divided into control group and meditation group by random number table method.The control group(n=30)received conventional treatment,and the meditation group(n=30)received meditation intervention for 8 months in addition to conventional treatment.Cognitive function and psychotic symptoms were assessed before admission and at the end of 8 months after treatment with the repeatability battery for the assessment of neuropsychological status(RBANS)and the brief psychiatric rating scale(BPRS)assesses psychotic symptoms.Results After intervention,the total scores of immediate memory and RBANS in the meditation group were higher than those before intervention,and the total scores of immediate memory,visual span,speech function and attention in the meditation group were higher than those in the control group,with statistical significances(P<0.05).After intervention,the total score of BPRS scale,anxiety and depression,inactivity,activation and hostile suspicion in the meditation group were lower than those before intervention,and the total score of BPRS scale,anxiety and depression,inactivity and activation scores in the meditation group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion Meditation intervention on the basis of conventional treatment for patients with residual schizophrenia can improve cognitive impairment and psychotic symptoms,and promote rehabilitation.
作者
顾燕
高红锐
杨湘红
戴晶璟
严珍
张晨
GU Yan;GAO Hongrui;YANG Xianghong;DAI Jingjing;YAN Zhen;ZHANG Chen(Shanghai No.1 Civil Administration Mental Health Center,Shanghai201105,China;Department of Psychiatry,Shanghai Mental Health Center,Shanghai Jiao Tong Univeristy School of Medicine,Shanghai200030,China)
出处
《中国医药导报》
CAS
2021年第7期91-94,共4页
China Medical Herald
基金
国家自然科学基金资助项目(81771450、81471358)。
关键词
冥想干预
残留型精神分裂症
认知功能
队列随访
Meditation intervention
Residual schizophrenia
Cognitive function
Cohort follow-up
