摘要
A Mn(Ⅲ) mediated radical reaction of new designed multi-functionalized 2-isocyano-6-alkenyl(alkynyl)benzonitriles with arylboronic acids has been developed.This reaction provides a method for the synthesis of pyrroloisoquinoline derivatives through the formation of two C-C bonds and one C-N bond via radical cascade cyclization in one step.
基金
the National Natural Science Foundation of China(Nos.21971174,21772137,21542015 and 21672157)
PAPD,the Project of Scientific and Technologic Infrastructure of Suzhou(No.SZS201708)
the Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions(No.16KJA150002)
Soochow University for financial support。
