摘要
目的应用心肌做功指数(MPI)智能检测技术测量正常中晚孕胎儿的右心心肌做功指数(RMPI)。方法回顾性选取2019年9月至2020年4月在汕头大学医学院第一附属医院产前检查的健康孕妇465例。将纳入研究的孕妇按照孕龄分为21+0~27+6周组172例、28+0~34+6周组169例、35+0~40+6周组124例。留取所有胎儿三尖瓣及肺动脉瓣口的血流频谱图像,应用MPI智能检测系统测量以获得胎儿的等容收缩期时间(ICT)、等容舒张期时间(IRT)、射血时间(ET)以及RMPI。分析不同孕龄的3组间各参数的差异,以及RMPI与孕龄之间的相关性。结果不同孕龄的3组间胎儿的RMPI、IRT差异有统计学意义(F=26.433、 34.359, P均<0.05), ICT、 ET差异无统计学意义(F=0.445、0.743,P均>0.05)。进一步两两比较,21+0~27+6周组与28+0~34+6周组的IRT、RMPI差异有统计学意义(P均<0.05),28+0~34+6周组与35+0~40+6周组的RMPI差异有统计学意义(P<0.05),21+0~27+6周组与35+0~40+6周组的IRT、RMPI差异有统计学意义(P均<0.05)。Pearson相关性分析结果显示,465例胎儿的RMPI与孕龄存在弱的线性相关关系(r=0.340,P<0.05)。结论 RMPI值受孕龄的影响,两者之间存在弱的线性相关关系。应用MPI智能检测技术测量正常胎儿RMPI为临床评估胎儿的心功能提供了一定的参考依据。
Objective To evaluate the right myocardial performance index(RMPI)of normal fetuses during the second and third trimesters of pregnancy by using an intelligent detection technology of myocardial performance index.Methods A total of 465 healthy pregnant women who underwent prenatal examination at the First Affiliated Hospital of Medical College of Shantou University from September 2019 to April 2020 were selected.According to the gestational age,the pregnant women included in the study were divided into three groups:172 cases in the 21+0~27+6 week group,169 in the 28+0~34+6 week group,and 124 in the 35+0~40+6 week group.The blood flow spectrum images of all fetal tricuspid valves and pulmonary valves were taken,and an intelligent detection system of myocardial performance index was used to measure the fetal isovolumetric contraction time(ICT),isovolumetric relaxation time(IRT),ejection time(ET),and RMPI.The differences of each parameter among the three groups with different gestational ages and the correlation between RMPI and gestational age were analyzed.Results There were significant differences in RMPI and IRT among the three groups(F=26.433,34.359,P<0.05 for both),although no significant differences were observed in ICT and ET among the three groups(F=0.445,0.743,P>0.05 for both).Further pairwise comparison showed that there were significant differences in IRT and RMPI between the 21+0~27+6 week group and 28+0~34+6 week group(P<0.05 for both),in RMPI between the 28+0~34+6 week group and 35+0~40+6 week group(P<0.05),and in IRT and RMPI between the 21+0~27+6 week group and 35+0~40+6 week group(P<0.05 for both).Pearson correlation analysis showed that there was a weak linear correlation between RMPI and gestational age(r=0.340,P<0.05).Conclusion RMPI is affected by gestational age,and there is a weak linear correlation between them.The measurement of RMPI in normal fetuses in the second and third trimesters of pregnancy by ultrasonic intelligent detection technology provide abasis for clinical evaluation of fetal cardiac function.
作者
陈绍琦
庄泽敏
陈庆子
谭学瑞
Chen Shaoqi;Zhuang Zemin;Chen Qingzi;Tan Xuerui(Department of Ultrasound,the First Affiliated Hospital of Shantou University Medical College,Shantou 515041,China;Clinical medicine research center,the First Affiliated Hospital of Shantou University Medical College,Shantou 515041,China;Shantou University Medical College,Shantou 515041,China)
出处
《中华医学超声杂志（电子版）》
CSCD
北大核心
2021年第2期188-192,共5页
Chinese Journal of Medical Ultrasound(Electronic Edition)
基金
高水平大学建设计划临床医学重点建设学科专项(2020)
广东省普通高校创新团队项目(自然类)(2019KCXTD003)
李嘉诚基金会交叉研究项目(2020LKSFG19B)
广东省高水平医院建设“登峰计划”项目—“领军人才”支撑计划项目(2019-2022)
国家自然科学基金面上项目(82073659)。
关键词
超声检查
产前
心肌做功指数
胎儿
孕龄
Ultrasonography,prenatal
Myocardial performance index
Fetus
Gestational age
