摘要
目的分析承德地区盐碘新标准实施后孕早期妇女碘营养状况及甲状腺功能调查。方法随机选取承德地区2018年1月至2020年3月在当地生活6个月以上孕早期妇女136例开展调查问卷,采集每位孕早期妇女家中食用碘、血样,分析盐碘、尿碘、甲状腺激素水平。结果2018—2019年孕早期妇女尿碘差异有统计学意义(P<0.05)。不同年份与不同尿磺水平组甲状腺疾病检出率(P>0.05)。结论承德地区盐碘新标准实施后,2019年孕早期妇女碘营养状况已明显改善,但摄入碘营养水平仍有少量不足;且碘摄入异常早期孕妇发生甲状腺疾病率高于碘适宜孕妇。
Objective To investigate the iodine nutritional status and thyroid function of women in early pregnancy after the implementation of a new standard of iodized salt in Chengde.Methods A total of 136 early pregnancy women who had lived in Chengde were randomly selected in this study from January 2018 to March 2020.A questionnaire survey was conducted.The iodized salt,urine and blood samples of the pregnant women were collected to analyze the salt iodine concentration,serum iodine,urinary iodine,serum thyroid stimulating hormone(TSH),free triiodothyronine(FT3),and free thyroxine(FT4).Results In 2018 and 2019,the iodized salt coverage rates were 96.97%and 98.57%,the non-iodized salt rates were 3.03%and 1.43%,the iodized salt qualification rates were 95.45%and 97.14%,and the qualified iodized salt consumption rates were 93.94%and 92.86%,respectively.In addition,the median of iodized salt consumption was 22.20 mg/kg and 25.51 mg/kg,in 2018 and 2019,respectively.There was a statistically significant difference in the median urine iodine from 2018 to 2019 among women in early pregnancy(P<0.05).The urinary iodine frequency distribution and detection rate of thyroid diseases of women in early pregnancy had no significant difference in 2018 and 2019,and no significant difference was found in the detection rate of thyroid diseases of women in low-iodine group,appropriate iodine group and high-iodine group(P>0.05).Conclusion After the implementation of a new standard of iodized salt in Chengde,the iodine nutritional status of early pregnant women in 2019 was significantly improved,but there was still a small amount of insufficient iodine intake.The incidence of thyroid diseases in early pregnant women with abnormal iodine intake was higher than that in early pregnant women with appropriate iodine intake.
作者
刘丹
汪冬梅
郝凤杰
王立东
LIU Dan;WANG Dongmei;HAO Fengjie;WANG Lidong(Department of Endocrinology,Chengde Central Hospital,Chengde,Hebei 067000,China)
出处
《公共卫生与预防医学》
2021年第2期144-146,共3页
Journal of Public Health and Preventive Medicine
基金
2014年承德市科学技术研究与发展计划项目“承德地区正常妊娠妇女甲状腺功能参考范围研究”(20142008)。
关键词
孕早期妇女
碘营养状况
甲状腺功能
Early pregnancy women
Iodine nutritional status
Thyroid function
