摘要
目的基于中医传承辅助平台系统,挖掘“半表半里”证-症-药规律研究。方法将半表半里相关医案录入中医传承辅助平台,构建数据库,采用改进互信息法、复杂系统熵聚类、无监督的熵层次取类等方法,分析“半表半里”的证-症-药规律。结果收集半表半里医案213个,涉及中医疾病53种、中医证候34个、症状253个、中药219味。从证候频次来看,少阳病证、热入血室证、热证、肝郁证、肝火炽盛证等出现频次较高;从症状频次来看,出现较多的症状为头汗、脉弦、脉数、寒热往来、发热等。从药物频数分析来看,甘草、柴胡、半夏、黄芩、生姜等出现频次较高。通过数据挖掘方法,得半表半里证常用药对为大枣+生姜、生姜+柴胡、黄芩+柴胡、半夏+柴胡+生姜、黄芩+柴胡+生姜,挖掘得到潜在药物组合3组,分别为谷芽_青蒿_佩兰_焦山楂;紫石英_刺蒺藜_肉苁蓉_白芍_熟地黄_川芎_当归;黄柏_苍术_藁本_萆薢。潜在症状组合1组为腰痛_身痛_脉浮_脉数_脉弦_头痛。结论小柴胡汤虽是半表半里的主要治疗底方,但不能将半表半里证等同于小柴胡汤证,半表半里证比小柴胡汤证范畴更大,病机涉及气血,病性寒热错杂,所治脏腑以中焦脾胃及肺脏为主。
Objective Based on TCMISS,to excavate the law research of syndrome-symptom-medicine in the semi-exterior and semi-interior phase.Methods The semi-exterior and semi-interior phase medical records are input into traditional Chinese medicine inheritance support system(TCMISS),and medical records database is constructed.The syndrome-symptom-medicine law of“semi-exterior and semi-interior phase”is analyzed by means of improved mutual information method of software integration,complex system entropy clustering and unsupervised entropy hierarchical classification.Results 213 medical cases involved 53 diseases,34 syndromes,253 symptoms and 219 medicines.From the frequency,Shaoyang syndrome,blood-heat of uterus,heat syndrome,stagnation of liver qi and relative superabundance of liver-fire are the higher frequency,from the frequency of symptoms,more symptoms are head sweat,taut pulse,rapid pulse,alternative chills and fever,fever and so on.According to the analysis of medicine frequency,Licorice,Bupleurum,Pinellia,Scutellaria,Ginger,etc.are the higher frequency.By data mining method,the commonly used medication pairs of semi-exterior and semi-interior phase are jujube+ginger,ginger+bupleurum,scutellaria+bupleurum,pinellia ternata+bupleurum+ginger,scutellaria+bupleurum+ginger.potential medicine combinations were found in three groups:grain bud_artemisia annua_perilan_burnt hawthorn,amethyst_tribulus tribulus_cistanche_paeonia paeoniae_rehmanniae rehmannii_ligusticum chuanxiong_angelica angelica;phellodendron_atractylodes_rhizoma_ligustilide_rhizoma dioscoreae hypoglaucae.Potential symptoms group 1 was pain in the lower back_body pain_pulse floating_pulse rapid_pulse taut_headache.Conclusion Although Xiaochaihu decoction is the main treatment base of semi-exterior and semi-interior phase,it cannot equate semi-exterior and semi-interior phase syndrome with Xiaochaihu decoction syndrome.Semi-exterior and semi-interior phase syndrome has a larger scope than Xiaochaihu decoction syndrome.Its pathogenesis involves qi and blood,and its pathogenesis is mixed with cold and heat.The main organs treated are the middle energizer(spleen and stomach)and lungs.
作者
姜侠
闫方杰
JIANG Xia;YAN Fangjie(School of Integrated Traditional Chinese and Western Medicine,Binzhou Medical University,Shandong Province,Yantai 264003,China;Department of Traditional Chinese Medicine,Shandong College of Traditional Chinese Medicine,Shandong Province,Yantai 264199,China)
出处
《中国中医药现代远程教育》
2021年第6期30-33,共4页
Chinese Medicine Modern Distance Education of China
基金
山东省中医药管理局中医药科技发展计划【No.2015-192】。
关键词
半表半里
医案
中医传承辅助系统
数据挖掘
semi-exterior and semi-interior
medical records
traditional Chinese medicine inheritance support system
data mining
