摘要
目的针对胃溃疡伴活动性出血患者,应用消化内镜联合四联疗法干预,分析临床治疗效果和再出血原因。方法选取2018年1月至2020年1月江苏省盐城市阜宁现代医院收治的68例胃溃疡伴活动性出血患者为研究对象,采用随机数字表法分常规组和试验组,各34例。常规组采用四联疗法干预,试验组在常规组基础上联合消化内镜干预。对比两组疗效,分析再出血原因。结果试验组治疗疗效优于常规组(P<0.05);影响再出血的单因素为:未联合内镜治疗、溃疡AI期、出血量、血小板水平、血红蛋白含量;通过Logistic回归分析发现,溃疡AI期、未联合内镜治疗、血红蛋白含量低是导致治疗后再出血的独立危险因素。结论消化内镜联合四联疗法干预,可提高胃溃疡伴活动性出血治疗疗效,再出血相关危险因素为未联合内镜治疗、血红蛋白含量低及溃疡AI期。
Objective For patients with gastric ulcer accompanied by active bleeding,digestive endoscopy combined with quadruple therapy was applied to intervene,and the clinical treatment effect and the cause of rebleeding were analyzed.Methods A total of 68 patients with gastric ulcer and active bleeding who were treated in Funing Modern Hospital of Yancheng City,Jiangsu Province from January 2018 to January 2020 were selected as the study subjects.The random number table method was used to divide the conventional group and the experimental group,34 cases each.The conventional group received quadruple therapy intervention,while the experimental group received combined digestive endoscopic intervention on the basis of the conventional group.The curative effect of the two groups was compared and the causes of rebleeding were analyzed.Results The therapeutic effect of the experimental group was better than that of the conventional group(P<0.05).Single factors affecting rebleeding were:non-combination endoscopic therapy,AI stage of ulcer,and amount of bleeding.Logistic regression analysis showed that AI stage,non-endoscopic therapy and low hemoglobin content were independent risk factors for rebleeding after treatment.Conclusion Intervention of digestive endoscopy combined with quadruple therapy can improve the efficacy of the treatment of gastric ulcer with active bleeding.Risk factors related to rebleeding are no endoscopic therapy,low hemoglobin content and AI stage of ulcer.
作者
胡广林
王盼盼
HU Guanglin;WANG Panpan(Funing Modern Hospital of Yancheng City,Jiangsu Province,Yancheng,Jiangsu 224400,China)
出处
《大医生》
2020年第24期16-18,共3页
Doctor
关键词
消化内镜
四联疗法
胃溃疡
活动性出血
有效率
再出血因素
digestive endoscopy
quadruple therapy
gastric ulcer
active bleeding
effective rate
rebleeding factors
