摘要
目的比较磁共振成像(magnetic resonance imaging,MRI)、超声、MRI联合超声3种检查方式诊断Ⅱ型胎儿成骨发育不全的效能,探讨MRI联合超声诊断Ⅱ型胎儿成骨发育不全的应用价值。方法回顾性分析进行产前检查并经术后病理证实Ⅱ型胎儿成骨不全的18例患者临床资料及影像学资料,以引产术后病理为金标准,比较超声、MRI、超声联合MRI 3种方法诊断胎儿成骨不全的敏感度、特异度、准确度、阳性预测值、阴性预测值。结果MRI检查准确诊断15例、超声检查准确诊断11例、超声联合MRI检查准确诊断17例,超声检查的诊断敏感度为61.11%、准确度为78.00%,MRI检查的诊断敏感度为83.33%、准确度为90.00%,综合考虑超声检查结果和MRI检查结果,超声联合MRI较超声检查的诊断敏感度上升至94.44%、准确度上升至96.00%。结论胎儿MRI联合超声诊断可提高目前超声诊断的诊断敏感度及准确度,有利于指导临床。
Objective To compare the diagnostic efficacy of magnetic resonance imaging(MRI),ultrasound and MRI combined with ultrasound in the diagnosis of typeⅡfetal osteogenesis imperfecta(OI)typeⅡ,so as to explore the application value of MRI combined with ultrasound in the diagnosis of fetal OI typeⅡ.Methods A retrospective analysis was performed on clinical data and imaging data of 18 patients with fetal OI typeⅡdiagnosed during antenatal examination and confirmed by postoperative pathological examination.With pathology of induction of labor as the gold standard,sensitivity,specificity,accuracy,positive predictive value,negative predictive value of ultrasound,MRI,and ultrasound combined with MRI in the diagnosis of fetal OI were calculated and compared.Results Accuracy of MRI,ultrasound and ultrasound combined with MRI in the diagnosis of fetal OI was confirmed in 11 cases,15 cases,and 17 cases,respectively.The diagnostic sensitivity of ultrasound was 61.11%,and the accuracy was 78.00%.The diagnostic sensitivity of MRI was 83.33%,with an accuracy of 90.00%.Considering ultrasound examination results and MRI findings,diagnostic sensitivity and accuracy of ultrasound combined with MRI increased to 94.44%and 96.00%respectively,as compared with ultrasound.Conclusion Fetal MRI combined with ultrasound can improve the diagnostic sensitivity and accuracy of current ultrasonography,which is helpful to guide clinical practice.
作者
付丽曼
李彦
陈舜珏
韩春庆
彭砾萱
宋忠华
FU Li-man;LI Yan;CHEN Shun-jue;HAN Chun-qing;PENG Li-xuan;SONG Zhong-hua(Department of Ultrasonography, the Fourth Hospital of Shijiazhuang, Hebei Province, Shijiazhuang 050011, China;Department of Radiology, the Third Hospital of Hebei Medical University, Hebei Province, Shijiazhuang 050051, China)
出处
《河北医科大学学报》
CAS
2021年第4期448-453,F0003,共7页
Journal of Hebei Medical University
基金
河北省重点科技研究计划(20191449)
河北医科大学学生创新性实验计划项目(USIP2019197)。
关键词
成骨不全
磁共振成像
超声检查
osteogenesis imperfecta
magnetic resonance imaging
ultrasonography
