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丙泊酚配伍依托咪酯在无痛人流术中的应用效果研究 被引量:4

Study on the Application Effect of Propofol and Etomidate in Painless Artificial Abortion
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摘要 目的分析丙泊酚配伍依托咪酯在无痛人流术中的应用效果。方法方便选取该院2017年12月—2019年12月期间收治的102例无痛人流患者,按其麻醉方式分组,其中51例接受丙泊酚麻醉(对照组),另51例接受丙泊酚联合依托咪酯混合液麻醉(观察组),比较患者治疗状况,如治疗过程中体征指标、患者术后睁眼时间、定向力和肌张力恢复时间、恢复行走时间及不良反应等。结果麻醉前两组RR、HR、MAP指标差异无统计学意义(P>0.05),麻醉后,观察组RR(15.32±5.21)次/min、HR(78.21±8.21)次/min、MAP(78.21±8.24)mmHg优于对照组RR(13.35±4.21)次/min、HR(72.21±10.21)次/min、MAP(71.32±10.21)mmHg,差异有统计学意义(t=12.762、10.902、2.662,P<0.05);观察组术后睁眼时间(3.21±0.65)min、定向力和肌张力恢复时间(5.20±1.02)min、恢复行走时间(15.21±1.35)min低于对照组(5.58±0.68)min、(7.98±1.01)min、(20.65±1.24)min,差异有统计学意义(t=9.652、10.325、15.201,P<0.05);观察组不良反应率13.73%比对照组15.69%低,差异无统计学意义(χ^(2)=0.078,P<0.05)。结论将丙泊酚与依托咪酯药物混合液应用于无痛人流术麻醉中,可在确保麻醉效果的基础上,提升麻醉安全性和苏醒速度,对术后恢复有利。 Objective To analyze the effect of propofol combined with etomidate in painless abortion.Methods Convenient select 102 patients with painless abortion admitted to the hospital from December 2017 to December 2019,and grouped according to their anesthesia methods,of which 51 received propofol anesthesia(control group),and the other 51 received propofol phenol combined with etomidate mixture anesthesia(observation group),compare the patient's treatment status,such as the physical signs during the treatment,the patient's postoperative eye-opening time,the recovery time of orientation and muscle tension,the recovery time of walking,and adverse reactions.Results Before anesthesia,there was no significant difference in RR,HR,and MAP indexes between the two groups(P>0.05).After anesthesia,the observation group had RR(15.32±5.21)times/min,HR(78.21±8.21)times/min,and MAP(78.21±8.24)mmHg was better than the control group RR(13.35±4.21)times/min,HR(72.21±10.21)times/min,MAP(71.32±10.21)mmHg,the difference was statistically significant(t=12.762,10.902,2.662,P<0.05);the observation group's postoperative eye-opening time(3.21±0.65)min,orientation and muscle tension recovery time(5.20±1.02)min,and walking recovery time(15.21±1.35)min were lower than those of the control group(5.58±0.68)min,(7.98±1.01)min,(20.65±1.24)min,the difference was statistically significant(t=9.652,10.325,15.201,P<0.05);the adverse reaction rate of the observation group was 13.73%,which was lower than the control group’s 15.69%,the difference was not statistical significance(χ^(2)=0.078,P<0.05).Conclusion The application of the drug mixture of propofol and etomidate in anesthesia for painless artificial abortion can improve the safety and recovery speed of anesthesia on the basis of ensuring the effect of anesthesia,which is beneficial to postoperative recovery.
作者 林晓妹 谭丽萍 冯祖莲 黎瑶瑶 陈汶 LIN Xiao-mei;TAN Li-ping;FENG Zu-lian;LI Yao-yao;Chen Wen(Department of Anesthesiology,Yangjiang People's Hospital,Yangjiang,Guangdong Province,529500 China;First Department of Urology,Yangjiang People's Hospital,Yangjiang,Guangdong Province,529500 China;Operating Room,Yangjiang City People’s Hospital,Yangjiang,Guangdong Province,529500 China)
出处 《中外医疗》 2021年第8期106-108,共3页 China & Foreign Medical Treatment
关键词 无痛人流 丙泊酚 依托咪酯 麻醉 Painless abortion Propofol Etomidate Anesthesia
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