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基于数据挖掘分析补土医派治疗情志病的用药规律 被引量:2

Analysis on the medication rule of invigorating the spleen medical school in the treatment of emotional diseases based on data mining
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摘要 目的挖掘补土医派治疗情志病的用药规律。方法以补土代表医家著作为资料来源,建立情志病用药数据库,对纳入的方剂中药进行因子分析和系统聚类分析。结果共纳入126个方剂,包括156味中药,用药频次达1110次。使用频数最高的5味中药是人参、当归、炙甘草、甘草、柴胡,使用频数最多的药物功效为补虚、解表、清热,药物四气以温、寒最常见,五味以辛、甘、苦味最多,归经以脾、肺、心、胃为主。因子分析中共提取9个公因子,累计方差贡献率为68.007%,系统聚类中将高频中药聚为6大类。结论补土医派情志病治则为虚则补益脾胃元气、实则泻其火,同时重升发脾胃阳气,虚实夹杂证则补脾胃、泻阴火、升清阳三者相合。 Objective To explore the medication rules of invigorating the spleen medical school in the treatment of emotional diseases.Methods The database of medication for emotional diseases was established with the works of the representative doctors of invigorating the spleen as the data source,and the factor analysis and systematic cluster analysis were carried out on the included prescriptions and Chinese medicine.Results A total of 126 prescriptions were included,involving 156 Chinese herbs.The drug use frequency was 1100 times.The top 5 frequently used herbs were Ginseng Radix et Rhizoma,Angelicae Sinensis Radix,Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle,Glycyrrhizae Radix et Rhizoma,Bupleuri Radix.The most frequently used efficacy of included herbs was tonifying deficiency,relieving superficies,and clearing heat.The four nature of drugs mainly included warm and cold.The five flavors mainly included pungent,sweet,and bitter.The channel tropism of Chinese herbs mainly included spleen,lung,heart,and stomach.Nine common factors were extracted from the factor analysis,the cumulative variance contribution rate was 68.007%,and the high-frequency herbs were classified into 6 categories in the systematic cluster analysis.Conclusion The principle of treatment of invigorating the spleen medical school for emotional diseases is treating deficiency syndrome with strengthening primordial qi of spleen and stomach method,treating excess syndrome with purging fire method.At the same time,they pay attention to the ascending and dredging of yang qi of spleen and stomach.While syndrome of intermingled deficiency and excess should combine the three principles of treatment,which are invigorating spleen and stomach,clearing yin-fire,ascending yang qi.
作者 李昀熹 林婉儿 杨玲玲 郑莉明 李艳 LI Yunxi;LIN Waner;YANG Lingling;ZHENG Liming;LI Yan(The Second Clinical Medical College,Guangzhou University of Chinese Medicine,Guangdong Province,Guangzhou510405,China;Department of Psychology and Sleep,Guangdong Provincial Hospital of Chinese Medicine,Guangdong Province,Guangzhou510405,China)
出处 《中国医药导报》 CAS 2021年第10期8-11,共4页 China Medical Herald
基金 国家自然科学基金青年科学基金项目(81804062)。
关键词 补土医派 情志病 用药规律 因子分析 聚类分析 Invigorating the spleen medical school Emotional diseases Medication rules Factor analysis Cluster analysis
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