摘要
目的基于数据挖掘近10年中医药辨治甲状腺功能减退症的文章,通过中医传承辅助平台(V2.5版)分析其用药规律,以期指导临床用药。方法检索中国知识资源总库(CNKI)、万方医学网、中文期刊服务平台(维普网)公开发表的近10年中医药治疗甲状腺功能减退症的文献,筛选并且构建相关组方数据库,整理药物,分析其用药规律。结果共筛选出133篇文献,140首中药处方,涉及中药203味,分析得出高频次中药、四气五味、归经、关联规则的常用药对、常用核心药对及新处方。结论CNKI、万方及维普数据库收录的近10年中医药治疗甲状腺功能减退症的文章,重视选择性温平、味甘、归脾肾肝经的中药,药物功效以温补肾阳、益气健脾为主,配伍淡渗利水、补血养阴,为临床治疗甲状腺功能减退症提供文献支撑。
Objective Based on data mining articles on the treatment of hypothyroidism in the traditional chinese medicine(TCM)in the past 10 years,analyze its medication rules through the TCM inheritance support platform(V2.5 version)in order to guide clinical medication.Methods To search the literature on the treatment of hypothyroidism with traditional Chinese medicine which was published in the CNKI,Wanfang Medical Network and VIP in the past 10 years,screening and constructing a database of relevant prescriptions,sorting out the drugs,and drawing the rules of medication.Results A total of 133 literatures and 140 Chinese medicine prescriptions were screened,involving 203 Chinese medicines.The analysis showed that the common drug pairs,common core drug pairs and new prescriptions of high-frequency Chinese medicine,four qi and five flavors,meridian distribution,and association rules were obtained.Conclusion Articles on the treatment of hypothyroidism with traditional chinese medicine included in CNKI,Wanfang Med Online and VIP in the past 10 years,paying attention to choosing the drug properties were warm and neutral,the drug tastes were sweet and pungent,and the meridians were spleen,kidney and liver.The efficacy of drug is mainly to warm and tonify kidney-yang,invigorate qi and spleen,eliminate dampness and diuresis,nourish blood and yin,provides strong literature support for clinical treatment of hypothyroidism.
作者
李秋莲
刘海鹏
王颜琦
范源
LI Qiulian;LIU Haipeng;WANG Yanqi;FAN Yuan(Yunnan University of Chinese Medicine,Kunming,650500,China;The Second Affiliated Hospital of Yunnan University of Chinese Medicine,Kunming,650216,China)
出处
《云南中医学院学报》
2020年第6期79-84,共6页
Journal of Yunnan University of Traditional Chinese Medicine
基金
国家自然科学基金项目(81360652)
云南省科技厅-云南中医学院应用基础研究联合专项[2017FF117(-008)]
云南省高校中西医结合防治甲状腺病重点实验室项目。
