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湿疹患者血清过敏原IgE、IgG结果分析

Analysis of serum allergen IgE and IgG in patients with eczema
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摘要 目的探讨湿疹患者与血清过敏原特异性IgE、IgG的关系,为临床防治提供依据。方法对某医院皮肤科就诊的湿疹患者血清sIgE、sIgG检测结果进行回顾性分析。结果研究对象共392例,其中男186例(47.45%),女206例(52.55%),平均年龄33.9岁。特异性IgE总阳性率为65.05%(255/392),其中前三位常见过敏原为户尘螨(35.20%)、霉菌组合(19.64%)、蟑螂(15.56%)。特异性IgG总阳性率为61.22%(240/392),阳性率较高的前三位是鸡蛋(39.54%)、西红柿(19.90%)、牛奶(17.09%)。IgE/IgG联合检测,其中有一项高于正常值的阳性率为83.67%(328/392)。过敏原特异性IgE、IgG阳性率在≤14岁组最高,分别为81.72%、89.25%。结论户尘螨、鸡蛋、西红柿、霉菌组合、牛奶、蟑螂等是湿疹常见致敏原,年龄是过敏所致湿疹重要影响因素。sIgE、sIgG结合检测可以提高过敏所致湿疹患者检出率。 Objective To explore the relationship between eczema patients and serum allergen specific IgE、IgG for clinical reference.Methods The serum sIgE and sIgG test results of eczema patients in a hospital were analyzed retrospectively.Results There are 392 cases and male patients are 186(47.45%)while female patients are 206(52.55%).The average age is 33.9.The total positive rate of IgE is 65.05%(255/392).The top three allergens are dust mite(35.20%),mold mix(19.64%)and cockroaches(15.56%).The total positive rate of IgG is 61.22%(240/392).The top three allergens are eggs(39.54%),tomatoes(19.90%)and milk(17.09%).There is one item higher than normal value(83.67%)(328/392)while tested combining IgE and IgG.The positive rate of specific IgE and IgG is the highest in the team under 14 years,81.72%、89.25%respectively.Conclusion Dust mite,eggs,tomatoes,mold mix,milk and cockroaches are factors for eczema.The age is the important factor.The combined test for sIgE and sIgG can improve the checking rate for those who are suffered eczema caused by allergy.
作者 陈镇 韦海鹏 张运莲 罗羡华 廖家顺 林小芳 CHEN Zhen;WEI Hai-peng;ZHANG Yun-lian;LUO Xian-hua;LIAO Jia-shun;LIN Xiao-fang(Beihai People's Hospital,Beihai,Guangxi 536000,China;Beihai Brand,Nanning Customs International Travel Healthcare Center,Beihai,Guangxi 536000,China;BeihaiVocational College,Beihai,Guangxi 536000,China)
出处 《皮肤病与性病》 2021年第2期161-163,共3页 Dermatology and Venereology
关键词 过敏原 湿疹 特异性IGE 特异性IGG Allergen Eczema Specific IgE Specific IgG
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