摘要
目的:了解骨科中老年就诊人群维生素D缺乏状况。方法:收集2014年11月至2020年1月在北京医院骨科就诊的55岁及以上中老年患者25-羟维生素D[25(OH)D]检测数据,回顾性分析该人群中不同性别、年龄段患者维生素D状况的差异。结果:共纳入3004例研究对象,年龄55~102岁,平均(71.1±9.7)岁,其中男725例,女2279例,血清25(OH)D为(17.77±9.92)μg/L,属于维生素D缺乏状态。55~64岁、65~74岁、75~84岁、85岁及以上维生素D分别为(19.66±9.77)μg/L、(18.34±9.78)μg/L、(16.19±9.51)μg/L、(14.74±10.49)μg/L,各年龄段之间差异均有统计学意义(F=29.357,P<0.05);全部研究对象血清25(OH)D水平达到严重缺乏程度占21.3%,缺乏占44.6%,不足占23.3%,充足占10.8%。男性维生素D水平由严重缺乏到充足不同程度分别为18.2%、44.8%、25.1%、11.9%,女性分别为22.2%、44.6%、22.7%、10.5%。男女患者维生素D严重缺乏发生率差异有统计学意义(χ^(2)=5.360,P<0.05)。结论:骨科中老年就诊人群随年龄增长维生素D水平呈下降趋势,严重缺乏者比例逐步增高,是进行干预的重点关注对象。
Objective To investigate the status of vitamin D deficiency in middle aged and elderly patients at an orthopedic department.Methods The data of 25-hydroxy vitamin D[25(OH)D]in patients aged over 55 years at an orthopedic department in Beijing Hospital from November 2014 to January 2020 were collected.The differences in serum 25(OH)D status were compared in different gender and age.Results A total of 3004 subjects were included with 725 males and 2279 females,ranged from 55 to 102 years old with an average of(71.1±9.7)years.The average serum 25(OH)D level was(17.77±9.92)ng/ml,which was diagnosed as vitamin D deficiency status.Serum 25(OH)D levels were(19.66±9.77)μg/L,(18.34±9.78)μg/L,(16.19±9.51)μg/L and(14.74±10.49)μg/L,at different age groups of 55-64,65-74,75-84,85 years and over,respectively,with statistically significant differences(F=29.357,P<0.05).Serum(OH)D levels of patients were severely deficient,deficient,insufficient and sufficient,with their proportion of 21.3%,44.6%,23.3%and 10.8%,respectively.The proportion of patients achieving from vitamin D levels severe deficiency to deficiency to insufficient to sufficient were 18.2%,44.8%,25.1%and 11.9%in men,and 22.2%,44.6%,22.7%and 10.5%in women,respectively.Conclusions The deficiency of vitamin D is prevalent in elderly patients visiting at orthopedic department.Serum 25-hydroxy vitamin D has a decreased trend along with age increasing,showing an increased trend of vitamin D deficiency.Patients with severe vitamin D deficiency are the focus for the intervention.
作者
石磊
步霄霄
张啟维
Shi Lei;Bu Xiaoxiao;Zhang Qiwei(Department of Orthopaedics,Beijing Hospital,National Center of Gerontology,National Health Commission,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China;Department of Clinical Laboratory,Beijing Hospital,National Center of Gerontology,National Health Commission,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China)
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2021年第4期487-490,共4页
Chinese Journal of Geriatrics
