摘要
半导体合成生物学是研究半导体技术与合成生物学之间协同作用的一门交叉学科。其涉及的活细胞-半导体材料杂合体系具有独特的能量和信号转导机制,不仅维持活细胞的代谢能力,而且保留半导体材料的光电学物理特性,在化工、通讯、计算、能源及医疗等领域具有广阔的应用前景。综述了半导体合成生物学在生物催化、智能生物传感以及新型DNA数据存储领域的最新研究进展,讨论了目前研究面临的技术难题及解决方案,旨在为合成生物学和半导体技术这两个影响化工发展的领域提供有价值的参考。
Semiconductor synthetic biology(also known as SemiSynBio,SSB)is an interdisciplinary subject that studies the synergy between semiconductor technology and synthetic biology.The living cell-semiconductor material hybrid system involved has a unique energy and signal transduction mechanism,which not only maintains the metabolic ability of living cells,but also retains the optoelectronic physical properties of semiconductor materials,and it has broad applications in the fields of chemical engineering,communication,computation,energy resource and medical treatment.This review outlines the state-of-the-art research advances of SSB in biocatalysis,intelligent biosensor and DNA data storage.In addition,forthcoming challenges and the corresponding solutions are also discussed.Overall,this review aims to provide valuable insights for advancing synthetic biology and semiconductor technology,two disciplines influencing chemistry engineering.
作者
王欣
赵鹏
李清扬
田平芳
WANG Xin;ZHAO Peng;LI Qingyang;TIAN Pingfang(College of Life Science and Technology,Beijing University of Chemical Technology,Beijing 100029,China;School of Food Science and Engineering,South China University of Technology,Guangzhou 510641,Guangdong,China)
出处
《化工学报》
EI
CAS
CSCD
北大核心
2021年第5期2426-2435,共10页
CIESC Journal
基金
国家重点研发计划项目(2018YFA0901800)
河北省重点研发计划项目(20322501D,19226509D)
北京市教育委员会科研计划-北京市自然科学基金项目(KZ201911417049)。
关键词
半导体合成生物学
细胞-无机材料界面
信号输入
信息存储
semiconductor synthetic biology
cell-inorganic material interface
signal input
information storage
