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口腔黏膜下纤维性变治疗进展 被引量:6

Progress in oral submucous fibrosis management
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摘要 口腔黏膜下纤维性变或称口腔黏膜下纤维化(oral submucous fibrosis,OSF)是一种慢性进行性并具有癌变倾向的口腔黏膜疾病。OSF的发病具有明显的地域性特点,在我国多发于湖南、台湾、海南等有咀嚼槟榔习惯的地区。自OSF1952年被报道发现至今,OSF治疗与癌变预防一直是国内外研究的热点。目前OSF的诊断已有较为一致的标准,但对于OSF的治疗尚未形成统一的意见。OSF作为一种治愈难度大、治疗过程长的疾病,在治疗过程中结合病人主诉,满足病人需求非常重要。本文拟从解决病人主诉的角度,对各种疗法进行综述。 Oral submucous fibrosis(OSF)is a chronic progressive oral mucosal disease which has a tendency of carcinogenesis.The onset distribution of OSF has notable regional features,and mostly happens in Hunan,Taiwan,Hainan of China where betel chewing is much common.Since OSF was reported in 1952,the management and cancer prevention have become the focus of domestic and foreign research.There have been an unanimous standard in the diagnosis of OSF but not a consensus in its management for now.To meet the needs of patients in accordance with their complains is important as OSF is difficult to cure and requires a long therapeutic course.This paper summarizes a wide range of management in the angle of patients`complains.
作者 李臻明 周晌辉 LI Zhenming;ZHOU Shanghui(Department of Oral&Maxillofacial-Head&Neck Oncology,College of Stomatology,Shanghai Ninth People’s Hospital,Shanghai Jiaotong University School of Medicine,National Clinical Research Center for Oral Diseases,Shanghai Key Laboratory of Stomatology&Shanghai Research Institute of Stomatology.Shanghai 200011,China)
出处 《中国中西医结合耳鼻咽喉科杂志》 2021年第2期156-160,共5页 Chinese Journal of Otorhinolaryngology in Integrative Medicine
基金 上海交通大学医工交叉研究基金面上项目(YG2016MS04) 上海市浦江人才计划(D类)(18PJD026)。
关键词 口腔黏膜下纤维性变 癌前病变 治疗 张口受限 槟榔 oral submucous fibrosis precancerous lesions management trismus betel nut
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