摘要
目的:研究安康市2009~2019年幽门螺杆菌(HP)感染流行病学现状及与非酒精性脂肪性肝病(NAFLD)发病的相关性,为实施健康安康战略提供疾病预防的科学依据及基础数据。方法:对2009年6月~2019年6月安康市中医医院消化内科门诊就诊的41187例患者进行^(13)C-尿素呼气试验检测,并对HP现症感染患者情况进行多因素分析,同时收集近3年10786例患者肝脏彩超、血脂、心电图数据,分析与HP感染的相关性。结果:受试患者中HP现症感染9906例,感染率均值为24.05%,其中男性感染率24.56%,女性感染率23.54%;中老年人群感染率较高,为28.62%;感染人群中农民和退休人员比例较高,为27.10%;使用纯净水的群体感染率较低,为17.05%;每周外出就餐次数>1次以上者感染率较高,为35.62%;吸烟群体易感性下降,为18.14%;近3年HP感染合并NAFLD患者为32.81%。结论:近10年安康地区HP平均现症感染率为24.05%,2013年后整体呈现下降趋势,与全国比较显著降低,总体呈现平稳趋势。
Objective:To study the epidemiological status of Helicobacter pylori(HP)infection in Ankang city from 2009 to 2019,and the multi-factor analysis of the incidence of non-alcoholic fatty liver disease(NAFLD),so as to provide a scientific basis for disease preventing for the implementation of the health and well-being strategy and basic data.Methods:From June 2009 to June 2019,a total of 41187 patients who visited the outpatient department of the tastroenterology department of our hospital were examined by ^(13)C-urease breath test,and a multi-factor analysis was performed on patients with current HP infection,analysising the correlation between liver color Doppler ultrasound,blood lipids,electrocardiogram data and HP infection in 10786 patients in recent three years.Results:Among the examined patients,9906 people were infected with HP,with an average infection rate of 24.05%,of which the male infection rate was 24.56%,and the female infection rate was 23.54%.The infection rate of the middle-aged and elderly population was higher,28.62%;among the infected population,farmers were farmers.The proportion of retirees and retirees is relatively high,27.10%;the infection rate of the group using purified water is lower,17.05%.And the infection rate of those who eat out more than once a week is higher,which is 35.62%.Also,the susceptibility of smoking groups is reduced,and the rate was 18.14%.The rate of HP infection and NAFLD patients was 32.81%in the past three years.Conclusion:In the past 10 years,the average current infection rate of HP in Ankang is 24.05%.After 2013,it has shown a downward trend,which is significantly lower than that of the whole country.The overall trend is stable.In the future,it is necessary to optimize the sterilization plan to study the city's drug resistance in recent years.
出处
《中西医结合肝病杂志》
CAS
2021年第5期445-448,共4页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金
安康市科技局项目(No.2018AK03-03)
陕西省科技厅项目(No.2018KJXX-072)
安康市科技局项目(No.2019AK2019S-F-14)
国家重点研发计划课题(No.2018YFC1344504)
陕西省科技厅项目(No.2021SF-233)。
