摘要
Dear Editor,Metastasis leads to a poor prognosis of patients with esophageal squamous cell carcinoma(ESCC).1-3 but the study on cancer metastasis has been hampered by a lack of reliable cell and animal models.Systematic identification and functional validation of metastasis-associated long non-coding RNAs(lncRNAs)and microRNAs(miRNAs),as well as-their interactions in ESCC are urgently needed.
基金
supported by National Natural Science Foundation of China(Project Nos.82073196,81773085,31961160727,81803551,81973339)
Guangdong Natural Science Research Grant(2021 Al 31157080)
Guangdong Innovative and Entrepreneurial Research Team Program(Project No.2013Y113)
Guangzhou Science and Technology Project(201904010061)
Zhuhai Innovative and Entrepreneurial Research Team Program(Project No.ZH01110405160015PWC)
National Key R&D Program of China(2017YFA0505100)
the Fundamental Research Funds for the Central Universities(21620429).