摘要
目的分析全甲状腺切除术和次全切除术治疗甲亢合并甲状腺癌的效果及对心脏功能和肝功能的影响。方法选取2018年4月至2019年4月于本院接受治疗的50例甲亢合并甲状腺癌患者作为研究对象,按照治疗方法不同分为对照组(n=24)和实验组(n=26),对照组给予次全切除术,实验组给予全甲状腺切除术,比较两组患者治疗效果(手术时间、术中出血量、住院时间、短暂性甲状腺功能减退情况),手术前后心脏功能[高峰充盈率(PFR)、左心室射血分数(LVEF)]和肝功能[丙氨酸转氨酶(ALT)、谷氨酰基转移酶(GGT)]及并发症发生情况。结果治疗后,实验组手术时间、住院时间短于对照组(P<0.05);治疗后,实验组术中出血量低于对照组(P<0.05);治疗后,实验组短暂性甲状腺功能减退发生率高于对照组(P<0.05)。术后,实验组PFR、LVEF、ALT、GGT均低于对照组(P<0.05)。术后,实验组并发症总发生率低于对照组(P<0.05)。结论全甲状腺切除术治疗甲亢合并甲状腺癌效果明显优于次全切除术,可明显改善心脏功能和肝功能,降低并发症发生率。
Objective To analyze the effect of total thyroidectomy and subtotal thyroidectomy on hyperthyroidism combined with thyroid cancer and its influence on heart function and liver function.Methods 50 patients with hyperthyroidism and thyroid cancer who were treated in our hospital from April 2018 to April 2019 were selected as the study subjects.According to the treatment methods,they were divided into control group(n=26)and experimental group(n=24).The control group was given subtotal resection,the experimental group was given total thyroidectomy,and the treatment effects(operation time,intraoperative hemorrhage,hospitalization time,transient thyroidectomy),cardiac function[peak filling rate(PFR),left ventricular ejection fraction(LVEF)],liver function[alanine aminotransferase(ALT),glutamyltransferase(GGT)]before and after operation and complications rates were compared between the two groups.Results After treatment,the operation time and hospitalization time of the experimental group were shorter than those of the control group(P<0.05);the intraoperative blood output of the experimental group was lower than that of the control group(P<0.05);the number of transient hypothyroidism in the experimental group was more than that of the control group(P<0.05).PFR,LVEF,ALT and GGT in the experimental group were lower than those in the control group(P<0.05).The total incidence of complications in the experimental group was lower than that in the control group(P<0.05).Conclusion Compared with subtotal thyroidectomy in the treatment of hyperthyroidism and thyroid cancer,total thyroidectomy is more effective,which can significantly improve the heart function and liver function,and reduce the incidence of complications.
作者
黄珊
何辉
HUANG Shan;HE Hui(Second Department of Surgery,Guangning People's Hospital,Zhaoqing,Guangdong,526300,China)
出处
《当代医学》
2021年第15期105-107,共3页
Contemporary Medicine
基金
肇庆市科技创新指导类项目(201904030836)。
关键词
甲亢合并甲状腺癌
全甲状腺切除术
次全切除术
治疗效果
Hyperthyroidism with thyroid cancer
Total thyroidectomy
Subtotal resection
Therapeutic effect
