摘要
目的探究丙泊酚复合舒芬太尼在老年腹腔镜胆囊切除术中的应用效果及对患者认知功能与术后恢复情况的影响。方法选择2018年3月至2019年2月收治的91例老年腹腔镜胆囊切除术患者为研究对象,通过随机数字表方式将其分为对照组(n=45,丙泊酚复合瑞芬太尼)和观察组(n=46,丙泊酚复合舒芬太尼)。比较两组的MMSE评分、术后恢复情况、不良反应总发生率、OAAS评分、血流动力学指标。结果术后6 h,观察组的MMSE评分高于对照组(P<0.05)。观察组的苏醒时间、自主呼吸恢复时间、定向力恢复时间均短于对照组(P<0.05)。观察组的不良反应总发生率低于对照组(P<0.05)。拔管后1、3 h,观察组的OAAS评分高于对照组(P<0.05)。拔管时、拔管后5 min,对照组的心率、舒张压、收缩压与拔管前5 min比较,差异有统计学意义(P<0.05);拔管后5 min,两组的心率、舒张压、收缩压比较,差异有统计学意义(P<0.05)。结论丙泊酚复合舒芬太尼用于老年腹腔镜胆囊切除术患者中的临床效果显著,患者的认知功能不会受到影响,且在短时间内便可苏醒,恢复自主呼吸及定向力。
Objective To explore the application effect of propofol combined with sufentanil in elderly patients undergoing laparoscopic cholecystectomy and its influences on cognitive function and postoperative recovery.Methods A total of 91 elderly patients undergoing laparoscopic cholecystectomy treated from March 2018 to February 2019 were selected as the study objects.The patients were divided into control group(n=45,propofol combined with remifentanil)and observation group(n=46,propofol combined with sufentanil)by random number table.MMSE score,postoperative recovery,total incidence of adverse reactions,OAAS score and hemodynamic indexes were compared between the two groups.Results At 6 h after operation,MMSE score of the observation group was higher than that of the control group(P<0.05).The recovery time,recovery time of spontaneous respiration and recovery time of directional force in the observation group were shorter than those in the control group(P<0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).At 1 and 3 h after extubation,the OAAS score in the observation group were higher than those in the control group(P<0.05).The heart rate,diastolic pressure and systolic pressure at extubation and 5 min after extubation in the control group were compared with those 5 min before extubation,and the differences were statistically significant(P<0.05);at 5 min after extubation,there were significant differences in heart rate,diastolic pressure and systolic pressure between the two groups(P<0.05).Conclusion The clinical effect of propofol combined with sufentanil in elderly patients undergoing laparoscopic cholecystectomy is significant.The cognitive function of the patients will not be affected,and the patients can wake up in a short time,restore spontaneous breathing and orientation.
作者
黄波
杨卫华
朱晓琳
HUANG Bo;YANG Weihua;ZHU Xiaolin(Anesthesiology Department,Puyang People's Hospital,Puyang 457000,China)
出处
《临床医学研究与实践》
2021年第15期81-83,共3页
Clinical Research and Practice
