摘要
目的:探讨增液承气汤联合乳果糖治疗化疗后便秘患者的临床疗效。方法:选取泰州市中医院肿瘤科收治的80例恶性肿瘤化疗便秘患者作为研究对象,采用随机数字表分为中医组和对照组各40例,对照组给予乳果糖治疗,中医组在对照组基础上加用增液承气汤治疗,对比两组治疗前后的临床症状评分、Bristol粪便性状评分及临床疗效。结果:治疗前,两组的各项临床症状评分差异无统计学意义(P>0.05),治疗后,中医组患者的排便频率、粪便性状、排便困难、使用泻剂、排便时间、腹胀评分均低于对照组(P<0.05);治疗前,两组的Bristol评分差异无统计学意义(P>0.05),治疗后,中医组患者的Bristol评分均高于对照组(P<0.05);治疗后,中医组痊愈率50.00%(20/40)、显效率32.50%(13/40)、有效率17.50%(7/40),对照组痊愈率25.00%(10/40)、显效率47.50%(19/40)、有效率22.50%(9/40)、无效率5.00%(2/40),中医组优于对照组(P<0.05)。结论:中医增液承气汤联合乳果糖治疗化疗后便秘患者能显著改善临床症状,提高临床效果。
Objective:To explore the clinical effect of Zengye Chengqi Decoction combined with lactulose in the treatment of constipation after chemotherapy.Methods:80 patients with constipation after chemotherapy of malignant tumors were randomly divide into the TCM group and the control group,with 40 cases in each group.The control group was treated with lactulose;on which basis,the TCM group was also treated with Zengye Chengqi Decoction.The clinical symptom scores and Bristol fecal trait scores were compared before and after the treatment in the two groups,and the clinical effect was compared between the two groups.Results:There were no statistical differences in clinical symptom scores between the two groups before the treatment(P>0.05);after the treatment,defecation frequency,stool feature,difficulty in defecation,laxative application,defecation time and abdominal bloating scores were lower in the TCM group than those in the control group(P<0.05).There was no significant difference in Bristol score between the two groups before the treatment(P>0.05);the Bristol score was higher in the TCM group than that in the control group after the treatment(P<0.05).The cure rate was 50.00%(20/40),the marked efficiency rate was 32.50%(13/40),and the effective rate was 17.50%(7/40)in the TCM group,which were significantly higher than 25%(10/40),47.5%(19/40)and 22.5%(9/40)correspondingly in the control group(P<0.05).The inefficient rate was 5%(2/40)in the control group.Conclusion:Zengye Chengqi Decoction combined with lactulose can significantly improve clinical symptoms and improve clinical effects in patients with constipation after chemotherapy.
作者
方锦舒
朱宝龙
翟萍萍
FANG Jinshu;ZHU Baolong;ZHAI Pingping(Oncology Department, Taizhou Hospital of TCM, Taizhou 225300, China)
出处
《中医药学报》
CAS
2021年第5期79-82,共4页
Acta Chinese Medicine and Pharmacology
基金
江苏省中医消化病临床医学研究中心项目(BL2014100)。
关键词
中医
便秘
增液承气汤
乳果糖
临床效果
TCM
Constipation
Zengye Chengqi Decoction
Lactulose
Clinical effect
