摘要
目的研究呼吸重症监护室(RICU)患者下呼吸道感染鲍氏不动杆菌的危险因素及耐药性。方法60例发生下呼吸道感染的RICU患者进行研究,均进行鲍氏不动杆菌样本培养,对感染鲍氏不动杆菌的危险因素和耐药进行分析。结果所有患者均检验出病原菌,共有68株。包括真菌、革兰阳性菌和革兰阴性菌,分别为41株、25株、2株,占比分别为60.29%、36.76%、2.94%。免疫球蛋白G(IgG)下降、多人病房、危重症监护时间>2周、抗菌药物更换次数>3次为下呼吸道感染鲍氏不动杆菌的影响因素,差异具有统计学意义(P<0.05)。头孢他啶、头孢曲松、氨曲南等属于高耐药性,左氧氟星沙、替加环素、阿米卡星等属于低耐药性。结论在RICU中下呼吸道感染鲍氏不动杆菌最多,其中免疫功能指标IgG、隔离措施等原因是引起下呼吸道感染鲍氏不动杆菌的危险因素。
Objective To study the risk factors and drug resistance of Acinetobacter baumannii infection in lower respiratory tract of respiratory intensive care unit(RICU)patients.Methods 60 cases of RICU patients with lower respiratory tract infections were studied,all of which were cultured with Acinetobacter baumannii samples to analyze the risk factors and drug resistance of Acinetobacter baumannii infection.Results All patients were detected 68 strains of pathogenic bacteria,including 41 strains of fungi,25 strains of gram-positive bacteria and 2 strains of gram-negative bacteria,accounting for 60.29%,36.76%,and 2.94%respectively.Decreased immunoglobulin G(IgG),multiple wards,duration of intensive care unit>2 weeks,and antibiotic replacement times>3 times were influencing factors for lower respiratory tract infection with Acinetobacter baumannii,and the difference was statistically significant(P<0.05).Ceftazidime,ceftriaxone,and aztreonam are highly resistant,while levofloxacin,tigecycline,and amikacin are low resistant.Conclusion Acinetobacter baumannii infection in lower respiratory tract is most common in RICU.Among them,the immune function index IgG,isolation measures and other reasons are the risk factors for Acinetobacter baumannii infection in lower respiratory tract.
作者
黄慕超
吴利秋
姚淑芳
HUANG Mu-chao;WU Li-qiu;YAO Shu-fang(Guangzhou Xinhai Hospital,Guangzhou 510000,China)
出处
《中国实用医药》
2021年第14期208-210,共3页
China Practical Medicine
关键词
呼吸危重症监护
重症患者
下呼吸道
鲍氏不动杆菌
危险因素
耐药性
Respiratory intensive care unit
Critically ill patients
Lower respiratory tract
Acinetobacter baumannii
Risk factors
Drug resistance
