摘要
目的了解长期接触低剂量电离辐射的放射工作人员外周血淋巴细胞微核率的总体水平,为采取相应的放射防护措施提供依据。方法以2019年1—12月504名资料完整的在岗放射工作人员为放射组,以岗前职业健康检查拟从事放射工作的105名健康成年人为对照组,2组均采用常规培养法测定周围血淋巴细胞微核率,分析比较检测结果。结果放射组微核率高于对照组(P<0.001);女性放射工作人员微核率高于男性(P<0.01);不同年龄组微核率差异有统计学意义(P<0.05),其中年龄41~50岁的微核率高于21~30岁(P<0.05);不同工龄组微核率差异有统计学意义(P<0.05),其中21~30年的微核率高于0~10年(P<0.05);不同工种间的微核率差异有统计学意义(P<0.01),放射治疗岗位人员的微核率较其他岗位最高;不同级别的单位放射工作人员微核率中,市级医院最高,其中省级医院与企业(P<0.05)、市级医院之间(P<0.01)的微核率的差异有统计学意义。结论放射工作人员的微核率高于非接触人员,女性的微核率高于男性,放射治疗的工作人员的微核率较高,应加强对此类人群的放射防护与日常管理。
Objective To investigate the micronucleus rate of peripheral blood lymphocytes in radiation workers exposed to chronic low dose ionizing radiation in Jiangsu province to adopt corresponding protective measures.Methods From January to December 2019,504 in-service radiation workers were taken as the radiation group,105 healthy adults who were to be engaged in radiation work by pre-job occupational health examination were served as the control group.We compared the micronucleus rate of peripheral blood lymphocytes measured by conventional culture.Results The micronucleus rate in the radiation group was significantly higher than that in the control group(P<0.001)and the micronucleus rate in the female radiation workers was higher than that in the male(P<0.01);The difference of micronucleus rate in different age groups was statistically significant(P<0.05),among which aged 41~50 years being higher than that of those aged 21~30 years.Besides,The difference of micronucleus rate between different working age groups was statistically significant(P<0.05),with higher rates in the 21~30 year range than in the 0~10 year range.(P<0.05).Differential micronucleus rates among different types of work were statistically significant(P<0.01),with the highest rate of micronucleus among staff in radiotherapy positions compared to other positions.What’s more,the highest rate of micronucleus among radiology staff in units of different levels was found in municipal hospitals,with statistically significant differences in micronucleus rates between provincial hospitals,enterprises(P<0.05)and municipal hospitals(P<0.01).Conclusion The micronucleus rate of radiation workers was significantly higher than that of non-contact personnel,and the micronucleus rate of female radiation workers is higher than that of men.Moreover,the highest rate was found among radiation workers.Therefore,radiation protection and daily management of this population should be strengthened.
作者
王秋雅
熊晓芸
张恒东
WANG Qiuya;XIONG Xiaoyun;ZHANG Hengdong(Jiangsu Provincial Center for Disease Control and Prevention,Nanjing 210046 China)
出处
《中国辐射卫生》
2021年第1期5-9,共5页
Chinese Journal of Radiological Health
关键词
放射工作人员
淋巴细胞
微核率
电离辐射
Radiation Workers
Lymphocytes
Micronucleus Rate
Ionizing Radiation
