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稳定型心绞痛病人血清心肌素、和肽素水平与急性心肌梗死发生的相关性 被引量:6

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摘要 目的检测稳定型心绞痛(SAP)病人血清心肌素、和肽素水平,并探讨其与急性心肌梗死(AMI)发生的相关性。方法选取2017年11月—2019年11月于邯郸市第一医院住院治疗的183例SAP病人为研究对象,根据有无发生AMI将病人分为两组,其中未发生AMI病人(单纯SAP组)112例,发生AMI病人(发生AMI组)71例。比较两组一般资料、糖脂代谢指标,采用酶联免疫吸附试验(ELISA)法检测SAP病人血清心肌素、和肽素水平,分析发生AMI病人血清心肌素、和肽素水平与糖脂代谢指标的相关性,并分析SAP病人发生AMI的影响因素。结果两组性别、年龄、血肌酐、高血压、高血脂比较,差异均无统计学意义(P>0.05);发生AMI组心肌素、和肽素、体质指数(BMI)、空腹血糖(FPG)、低密度脂蛋白胆固醇(LDL-C)、三酰甘油(TG)、总胆固醇(TC)明显高于单纯SAP组(P<0.05),高密度脂蛋白胆固醇(HDL-C)明显低于单纯SAP组(P<0.05);发生AMI病人血清心肌素、和肽素水平与FPG、LDL-C、TG、TC均呈正相关(P<0.05),与HDL-C呈负相关(P<0.05);心肌素、和肽素是SAP病人发生AMI的危险因素,HDL-C是SAP病人发生AMI的保护因素。结论SAP发生AMI病人血清心肌素、和肽素水平高于单纯SAP病人,心肌素、和肽素水平的变化对AMI的发生有重要意义,SAP病人血清心肌素、和肽素水平升高会增加AMI发生的风险。
机构地区 邯郸市第一医院
出处 《中西医结合心脑血管病杂志》 2021年第10期1712-1715,共4页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金 河北省医学科学研究重点课题计划项目(No.20181714)。
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