摘要
目的探讨磁共振(MRI)影像特征评价较低级别胶质瘤患者预后的临床价值。方法回顾性分析2012-01—2016-12在郑州大学第一附属医院接受手术治疗的119例Ⅱ级、Ⅲ级脑胶质瘤患者的影像学和临床资料,采用Kaplan-Meier法计算总生存期(OS)和无进展生存期(PFS)的生存率。各预后因素生存率的比较采用Log-rank检验,多因素分析采用Cox回归。结果肿瘤的强化程度与卫星灶是影响较低级别胶质瘤患者预后的独立危险因素。肿瘤明显强化及肿瘤周围有卫星灶患者的OS(P<0.001)与PFS(P<0.001)均缩短。结论肿瘤明显强化以及肿瘤周围有卫星灶患者的预后较差,可以通过影像特征来预测较低级别胶质瘤患者的预后。
Objective To investigate the clinical value of Magnetic resonance imaging(MRI)features in evaluating prognosis of patients with lower-grade gliomas(LGGs).Methods A retrospective study was performed on 119 surgical patients of GradeⅡ/ⅡI gliomas with imaging and clinical data in the First Affiliated Hospital of Zhengzhou University from January 2012 to December 2016.The Kaplan-Meier method was used to calculate overall survival(OS)and progression-free survival(PFS).Log rank test was used to compare the survival rate of these prognostic factors.Cox regression was used for multivariate analysis.Results Enhancement quality and satellites were independent risk factors influencing prognosis of patients with LGGs.Tumors with marked enhancement or satellites were associated with worse OS(P<0.001)and PFS(P<0.001).Conclusion Tumors with marked enhancement and tumors with satellites have poor prognosis,and we can predict the outcome of patients with LGGs by imaging features.
作者
孙涛
湛允波
阎静
刘献志
Sun Tao;Zhan Yunbo;Yan Jing;Liu Xianzhi(Department of Neurosurgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)
出处
《河南外科学杂志》
2021年第3期3-7,共5页
Henan Journal of Surgery
基金
国家自然科学基金项目(U1804172)。
