摘要
目的建立硅烷化-气相色谱法测定工作场所空气中氯乙酸浓度的方法。方法于2020年3月,用硅胶管采集空气中的氯乙酸,样品干燥后,室温下经乙腈:N,O-双(三甲基硅烷)三氟乙酰胺(2:1,V/V)解吸及硅烷化反应后,由气相色谱定量分析硅烷化产物。结果此方法在0~162.8μg/ml浓度范围内线性关系良好,线性方程:y=0.0118x,相关系数r=0.9997,方法的检出限为0.8μg/ml,最低检出浓度为0.05 mg/m^(3)(以采集15 L空气计),5次平行测定相对标准偏差(RSD)在0.5%~1.3%,空白加标回收率在98.6%~101.2%。结论该方法灵敏、简便、准确,可以用于工作场所空气中氯乙酸浓度的测定。
Objective A method to determine acrylic acid in workplace air was developed by silanization-gas chromatography.Methods In March 2020,chloroacetic acid in air were absorbed by silica gel tube,the samples were dried,then were desorbed and silanized by acetonitrile:N,O-bis(trimethylsilane)trifluoroacetamide(2∶1,V/V)at room temperature,allowed quantitative analysis of chloroacetic acid as its silanization product by gas chromatography.Results Calibration curve of the method was linear within the range 0-162.8μg/ml and showed good linearity with linear equation:y=0.0118x,r=0.9997.The determination limit of the method was 0.8μg/ml,and the minimum detection concentration was 0.05 mg/m^(3)(collect 15 L air).The relative standard deviation(RSD)was 0.5%-1.3%(n=5).Recoveries were between 98.6%-101.2%.Conclusion The results prove silanization-gas chromatography is an accurate,simple and high sensitive method for determining chloroacetic acid in workplace air.
作者
王鹏
任鸿
徐秋凉
曹艺耀
Wang Peng;Ren Hong;Xu Qiuliang;Cao Yiyao(Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou 310051,China)
出处
《中华劳动卫生职业病杂志》
CAS
CSCD
北大核心
2021年第4期299-302,共4页
Chinese Journal of Industrial Hygiene and Occupational Diseases
关键词
色谱法
气相
氯乙酸
工作场所
空气
硅烷化
Chromatography,gas
Chloroacetic acid
Workplace
Air
Silanization
