摘要
目的探讨连续热灌注治疗肺癌恶性胸腔积液的临床效果。方法66例肺癌恶性胸腔积液患者,根据随机分配的原则分为观察组和对照组,每组33例。对照组患者采用非连续热灌注的方式进行治疗,观察组患者则采用连续热灌注的方式进行治疗。对比两组患者生活质量评分、临床疗效、不良事件发生情况。结果观察组患者的躯体疼痛评分为(86.13±11.56)分,情感职能评分为(89.12±12.89)分,精神健康评分为(90.12±10.36)分,认知功能评分为(89.26±12.09)分,生理机能评分为(85.33±11.77)分;对照组患者的躯体疼痛评分为(73.59±10.26)分,情感职能评分为(74.18±10.61)分,精神健康评分为(71.45±11.48)分,认知功能评分为(74.89±12.12)分,生理机能评分为(71.78±12.15)分。观察组患者的躯体疼痛、情感职能、精神健康、认知功能、生理机能评分均高于对照组,差异有统计学意义(P<0.05)。观察组患者的治疗总有效率96.970%高于对照组的81.818%,差异有统计学意义(P<0.05)。观察组患者的不良事件发生率9.091%(3/33)低于对照组的30.303%(10/33),差异有统计学意义(P<0.05)。结论连续热灌注治疗肺癌恶性胸腔积液的临床效果良好,能够有效推进患者的治疗进展,是一种安全性较高的治疗方案,可延长患者的生存时间,提高患者的生活质量,具有较高的临床价值,值得临床推广使用。
Objective To discuss the clinical effect of continuous hyperthermic perfusion in the treatment of malignant pleural effusion of lung cancer.Methods A total of 66 patients with malignant pleural effusion of lung cancer were randomly divided into observation group and control group,with 33 cases in each group.The control group was treated with discontinuous hyperthermic perfusion,and the observation group was treated with continuous hyperthermic perfusion.The quality of life score,clinical efficacy and occurrence of adverse events were compared between the two groups.Results The physical pain score,emotional function score,mental health score,cognitive function score and physiological function score of the observation group were(86.13±11.56),(89.12±12.89),(90.12±10.36),(89.26±12.09),and(85.33±11.77)points,which were(73.59±10.26),(74.18±10.61),(71.45±11.48),(74.89±12.12)and(71.78±12.15)points of the control group.The physical pain score,emotional function score,mental health score,cognitive function score and physiological function score of the observation group were higher than those of the control group,and the difference was statistically significant(P<0.05).The total effective rate 96.970%of the observation group was higher than 81.818%of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse events 9.091%(3/33)of the observation group was lower than 30.303%(10/33)of the control group,and the difference was statistically significant(P<0.05).Conclusion Continuous hyperthermic perfusion shows good clinical effect on malignant pleural effusion of lung cancer,which can effectively promote the treatment progress,prolong the survival time,improve the quality of life with high clinical value.It is a high safety treatment scheme,and is worthy of clinical promotion and application.
作者
郑华
ZHENG Hua(Benxi Jinshan Hospital,Benxi 117000,China)
出处
《中国实用医药》
2021年第15期31-33,共3页
China Practical Medicine
关键词
连续热灌注
肺癌
恶性胸腔积液
Continuous hyperthermic perfusion
Lung cancer
Malignant pleural effusion
