摘要
设计合成了一个反应型的硼氟二吡咯(BODIPY)类荧光探针1,该探针以吡啶‑2‑羧酸苯酚酯基为识别基团。通过^(1)H NMR、^(13)C NMR和HRMS表征了1的结构,并解析了其晶体结构。光谱分析实验结果显示,探针1具有高的荧光量子产率(0.79),对Cu^(2+)具有较强的选择性识别性能,并能成功应用到生物细胞中Cu^(2+)的成像检测。
A fluorescent probe 1,based on boron fluoride dipyrrole(BODIPY)chromophore containing phenyl picolinate as a recognition moiety,was designed,synthesized,and characterized by^(1)H NMR,^(13)C NMR,HRMS and Xray diffraction.Probe 1 had a high fluorescence quantum yield(0.79),and could selectively and sensitively recognize Cu^(2+)from other cations by a fluorescence quenching method.The limit of detection of probe 1 was 0.15μmol·L-1.In addition,the recognition mechanism of the fluorescent response to copper ions was verified by HRMS in this work.CCDC:2062769.
作者
边永军
渠星宇
李芬芳
张政委
李建晴
陈勇强
沈珍
BIAN Yong‑Jun;QU Xing‑Yu;LI Fen‑Fang;ZHANG Zheng‑Wei;LI Jian‑Qing;CHEN Yong‑Qiang;SHEN Zhen(Department of Chemistry and Chemical Engineering,Jinzhong University,Jinzhong,Shanxi 030619,China;State Key Laboratory of Coordination Chemistry,School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210023,China)
出处
《无机化学学报》
SCIE
CAS
CSCD
北大核心
2021年第6期1089-1096,共8页
Chinese Journal of Inorganic Chemistry
基金
山西省高等学校科技创新项目(No.2019L0894)
晋中学院“1331工程”光电材料重点创新团队(No.jzxycxtd2017007)
山西省‘1331工程’重点创新团队建设计划(No.PY201817)
山西省高等学校教学改革创新项目(No.J2020317)
晋中学院教学改革创新项目(No.Jg202039)资助。
关键词
硼氟二吡咯亚甲基
铜离子
荧光探针
荧光猝灭
boron fluoride dipyrromethene
copper ion
fluorescent probe
fluorescence quenching
