摘要
目的观察阿立哌唑治疗精神分裂症伴抑郁的临床疗效。方法从我院随机挑选从2017年5月至2019年3月收治的86例精神分裂症伴抑郁患者作为研究对象,并随机把研究对象分为对照组(n=43)和试验组(n=43),给予对照组常规治疗,在对照组的基础上给予试验组阿立哌唑治疗。对两组患者HAMD评分、治疗效果、生活质量、不良反应发生情况进行观察。结果治疗后,试验组患者的HAMD评分低于对照组,生活质量评分及治疗总有效率高于对照组(P<0.05);治疗后试验组不良反应发生率是2.33%,明显低于对照组的11.63%(P<0.05)。结论对精神分裂症伴抑郁的患者给予阿立哌唑治疗,具有良好的临床治疗效果,可以有效缓解患者的抑郁症状,还可以提升患者的生活质量。
Objective To observe the clinical effect of aripiprazole on schizophrenia with depression.Methods Eighty-six patients with schizophrenia with depression were randomly selected from our hospital from May 2017 to March 2019 as the study subjects,and the subjects were randomly divided into control group(n=43)and experimental group(n=43),to give routine treatment to the control group and on the basis of the control group to give aripiprazole treatment to the experimental group.The HAMD scores,therapeutic effects,quality of life and adverse reactions of the two groups were observed.Results After treatment,the HAMD score of the experimental group was lower than that of the control group,the quality of life scores and the total effective rate of treatment were higher than that of the control group(P<0.05);after treatment,the adverse reaction rate of the experimental group was 2.33%,which was significantly lower than the control group 11.63%(P<0.05).Conclusion In the treatment of the patients with schizophrenia and depression,the treatment with aripiprazole is given,which has good clinical treatment effect,can effectively relieve the depressive symptoms of the patients,and can also improve the quality of life of the patients,and has higher popularization value.
作者
吕睿
LYU Rui(The First Ward of the Department of Geriatrics,Shenyang Mental Health Center,Shenyang 110168,China)
出处
《中国医药指南》
2021年第11期78-79,共2页
Guide of China Medicine
关键词
精神分裂症
抑郁
阿立哌唑
生活质量
Schizophrenia
Depression
Aripiprazole
Quality of life
