摘要
目的探讨对老年膝关节退行性骨关节炎应用关节置换治疗的效果及对生活质量的影响。方法选取2017年1月~2020年10月北京怀柔医院收治的膝关节退行性骨关节炎老年患者69例,根据随机数字表法分为保守组34例和手术组35例,保守组行药物保守治疗,手术组在保守组的基础上实施关节置换术治疗,比较两组膝关节功能、炎性因子水平、生活质量评分、临床疗效及术后并发症。结果两组膝关节评分、活动功能评分及AKS总分高于治疗前,差异有统计学意义(P<0.05);手术组的膝关节评分、活动功能评分、AKS总分及SF-36各维度评分高于保守组,TNF-α、CRP、TGF-β1水平低于保守组,差异有统计学意义(P<0.05);手术组的治疗总有效率为94.29%,高于保守组的76.47%,差异有统计学意义(P<0.05);手术组并发症发生率为5.72%,低于保守组的20.59%,差异有统计学意义(P<0.05)。结论对老年膝关节退行性骨关节炎应用关节置换治疗的效果确切,可促进膝关节功能恢复,减轻其炎性指标水平,提升其生活质量,且术后并发症发生率低,预后良好。
Objective To investigate the effect of joint replacement therapy on elderly knee degenerative osteoarthritis and its impact on quality of life.Methods A total of 69 elderly patients with knee degenerative osteoarthritis who were admitted to Beijing Huairou Hospital from January 2017 to October 2020 were selected.According to the random number table method,they were divided into 34 cases in the conservative group and 35 cases in the operation group.The conservative group was treated with drugs conservatively,and the operation group was treated with joint replacement on the basis of the conservative group.The knee joint function,inflammatory factor level,quality of life score,clinical efficacy and postoperative complications were compared between the two groups.Results The knee joint scores,motor function scores and AKS total scores between the two groups were higher than those before treatment,the difference was statistically significant(P<0.05);The knee joint score,activity function score,AKS total score,and SF-36 scores in each dimension of the surgical group were higher than those of the conservative group.The levels of TNF-α,CRP,and TGF-β1 were lower than those of the conservative group,the difference was statistically significant(P<0.05);The total effective rate of treatment in the surgical group was 94.29%,which was higher than 76.47%in the conservative group,the difference was statistically significant(P<0.05);The complication rate in the surgical group was 5.72%,which was lower than 20.59%in the conservative group,the difference was statistically significant(P<0.05).Conclusion The effect of joint replacement therapy on elderly knee degenerative osteoarthritis is definite,which can promote the recovery of knee joint function,reduce the level of inflammatory indexes,and improve the quality of life.The incidence of postoperative complications is low and the prognosis is good.
作者
盛子龙
徐伟
伍正根
彭明学
SHENG Zi-long;XU Wei;WU Zheng-gen;PENG Ming-xue(Department of Orthopedics,Beijing Huairou Hospital,Beijing 101400,China)
出处
《医学信息》
2021年第12期115-117,共3页
Journal of Medical Information
关键词
膝关节退行性骨关节炎
关节置换
生活质量
膝关节功能
炎性因子
Knee joint degenerative osteoarthritis
Joint replacement
Quality of life
Knee joint function
Inflammatory factors
