摘要
目的分析血清PCT与CRP共同检测在小儿支原体肺炎与细菌性肺炎鉴别诊断中的参考意义。方法该研究便利选取2018年3月—2020年3月该院收治的135例研究对象进行回顾性分析,其中45例为小儿支原体肺炎患儿,设为甲组,45例为细菌性肺炎患儿,设为乙组,45名为健康体检儿童,设为丙组,3组皆行血清PCT与CRP检测。对比分析3组患儿的血清PCT与CRP水平,统计检测情况,观察预后情况。结果丙组的血清PCT(0.03±0.01)ng/mL明显低于甲组(0.11±0.06)ng/mL、乙组(0.84±0.09)ng/mL,丙组的CRP(5.03±1.34)mg/L明显低于甲组(33.28±2.63)mg/L、乙组(73.20±3.11)mg/L,组间差异有统计学意义(F=132.346、28.321,P<0.05);乙组的PCT(0.84±0.09)ng/mL与CRP(73.20±3.11)mg/L明显高于甲组(0.11±0.06)ng/mL、(33.28±2.63)mg/L,组间差异有统计学意义(t=45.273、65.749,P<0.05)。血清PCT与CRP联合检测的阳性检出率为86.67%,高于单独血清PCT(58.89%)、CRP(66.67%),差异有统计学意义(χ^(2)=19.846,P<0.05)。在90例小儿支原体肺炎与细菌性肺炎患儿研究过程中,死亡10例,存活80例,其中生存组的血清PCT(3.11±0.47)ng/mL与CRP(26.34±5.03)mg/L明显低于死亡组(8.63±1.52)ng/mL、(115.36±18.63)mg/L,组间差异有统计学意义(t=24.964、34.787,P<0.05)。结论血清PCT与CRP共同检测有助于提高小儿支原体肺炎和细菌性肺炎的诊断鉴别,可作为评估标准,临床可进一步推广运用。
Objective To analyze the reference significance of co-detection of serum PCT and CRP in the differential diagnosis of mycoplasma pneumonia and bacterial pneumonia in children.Methods The study conveniently selected 135 subjects admitted to the hospital from March 2018 to March 2020 for retrospective analysis.Among them,45 were children with mycoplasma pneumonia in children,set as group A,and 45 were children with bacterial pneumonia,set as group B,45 children with healthy physical examination,set as group C,and all 3 groups were tested for serum PCT and CRP.The serum PCT and CRP levels of the three groups of children were compared and analyzed,the detection results were statistically analyzed,and the prognosis was observed.Results Serum PCT(0.03±0.01)ng/mL in group C was significantly lower than that in group A(0.11±0.06)ng/mL,group B(0.84±0.09)ng/mL,and CRP(5.03±1.34)mg/mL in group C was significantly lower than that of group A(33.28±2.63)mg/L and group B(73.20±3.11)mg/L,the difference between the groups was statistically significant(F=132.346,28.321,P<0.05);PCT(0.84±0.09)ng/mL and CRP(73.20±3.11)mg/L were significantly higher than group A(0.11±0.06)ng/mL,(33.28±2.63)mg/L,the difference between the groups was statistically significant(t=45.273,65.749,P<0.05).The positive diagnosis rate of combined detection of serum PCT and CRP was 86.67%, which was higher than that of serum PCT(58.89%) and CRP(66.67%), the difference was statistically significant (χ^(2)=19.846, P<0.05). During the study of 90 children with mycoplasma pneumonia and bacterial pneumonia, 10 cases died and 80 cases survived. The serum PCT (3.11±0.47) ng/mL and CRP (26.34±5.03) mg/L of the survival group were significantly lower in the death group (8.63±1.52) ng/mL, (115.36±18.63) mg/L, the difference between the groups was statistically significant(t=24.964, 34.787, P<0.05). Conclusion The combined detection of serum PCT and CRP can help improve the diagnosis and differentiation of mycoplasma pneumonia and bacterial pneumonia in children. It can be used as an evaluation standard and can be further promoted in clinical practice.
作者
顾蕊
GU Rui(Pediatrics Laboratory,the First Affiliated Hospital of Bengbu Medical College,Bengbu,Anhui Province,233000 China)
出处
《中外医疗》
2021年第12期164-167,共4页
China & Foreign Medical Treatment
关键词
小儿支原体肺炎
细菌性肺炎
血清降钙素原
血清C反应蛋白
Mycoplasma pneumonia in children
Bacterial pneumonia
Serum procalcitonin
Serum C-reactive protein
