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男性不育症危险因素的Meta分析 被引量:9

Meta analysis of risk factors for male infertility
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摘要 目的通过Meta分析探讨男性不育症的危险因素。方法检索国内外多个数据库,搜索建库至2020年5月的有关男性不育症危险因素研究的文献。应用RevMan 5.3软件对提取的资料进行分析。结果最终纳入13篇文献,Meta分析结果显示,有统计学意义的危险因素为熬夜4.64(1.26,17.11)、吸烟2.43(1.95,3.03)、从事高温作业3.40(1.81,6.37)、生殖系统疾病3.26(2.04,5.19)、婚外性生活史3.84(2.26,6.50)、缺乏锻炼2.16(1.27,3.67)、长时间使用电脑2.11(1.15,3.85)、食用粗制棉籽油史4.29(1.66,11.09)。结论熬夜、吸烟、从事高温作业、生殖系统疾病、缺乏锻炼、长期使用电脑、婚外性生活史、食用粗制棉籽油史是男性不育症的危险因素。 Objective To analyze the risk factors of male infertility through meta analysis. Methods Retrieve multiple databases at home and abroad, search for literatures on the risk factors of male infertility, and use RevMan 5.3 software to analyze the extracted data. Results A total of 13 articles were retrieved and adopted. Meta analysis results showed that the statistically significant risk factors were staying up late 4.64(1.26, 17.11), smoking 2.43(1.95, 3.03), engaged in high-temperature work 3.40(1.81, 6.37), reproductive system diseases 3.26(2.04, 5.19), history of extramarital sex life 3.84(2.26, 6.50), lack of exercise 2.16(1.27, 3.67), long-term use of computer 2.11(1.15,3.85), history of edible crude cottonseed oil 4.29(1.66, 11.09). Conclusions Staying up late, smoking, engaged in high-temperature work, reproductive system diseases, lack of exercise, long-term use of computer, history of extramarital sex life, history of edible crude cottonseed oil are risk factors for male infertility.
作者 张银 车晓艳 万婠 张恩思 ZHANG Yin;CHE Xiaoyan;WAN Wan;ZHANG Ensi(Nanjing Drum Tower Hospital Clinical College of Jiangsu University,Nanjing 210008,Jiangsu,China;Department of Andrology,Drum Tower Hospital Affiliated to Nanjing University School of Medicine,Nanjing 210008,Jiangsu,China)
出处 《中国性科学》 2021年第5期15-18,共4页 Chinese Journal of Human Sexuality
基金 南京市卫生科技医学重点科技发展项目(ZKX18015)。
关键词 男性不育症 危险因素 病例对照 META分析 Male infertility Risk factors Case control Meta analysis
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