摘要
目的研究腹膜透析(peritoneal dialysis,PD)患者左心室质量指数(left ventricular mass index,LVMI)进展的影响因素。方法回顾性分析199例在笔者医院置管并规律随访的PD患者。收集置管期间的心脏超声以及间隔12个月以上的第2次超声心动图结果,计算LVMI。记录患者第2次行超声心动图检查期间的相关临床指标,87例患者LVMI增加,定义为进展组,其余112例为LVMI稳定组。采用Logistic回归分析LVMI进展的影响因素。结果LVMI进展组体重指数(BMI)、收缩压、舒张压、甲状旁腺激素(PTH)、残余肾功能(RRF)、尿量(24h)、LVMI指标高于LVMI稳定组,左心室肥厚(left ventricular hypertrophy,LVH)发生率更高,而血红蛋白及血清白蛋白较低(P均<0.05)。多因素回归Logistic回归分析显示收缩压、血磷与LVMI进展呈正相关(OR分别为1.043、2.698,P<0.05),血红蛋白、血清白蛋白、RRF与LVMI进展呈负相关(OR分别为0.970、0.925、0.847,P<0.05)。结论PD患者的收缩压、血磷、血红蛋白、血清白蛋白、RRF与LVMI的进展相关。
Objective To investigate the influencing factors of the progression of left ventricular mass index(LVMI)in peritoneal dialysis(PD)patients.Methods Totally 199 Patients who underwent peritoneal dialysis catheter insertions and with regular medical follow-up in our hospital were enrolled into this retrospective study.Methods the velues of LVMI were determined by echocardiography evaluations(twice)at an interval of more than 12 months.All patients underwent the first echocardiography evaluations during the placement of peritoneal dialysis catheter.During the second echocardiography examination,the clinically relevant indexes were collected.The factors related to the progress on LVMI were analyzed by Logistic regression.LVMI was increased in 87 patients and not in 112 patients,and was grouped accordingly.Results Compared with the group in which LVMI was not increased,the increased group patients had higher body mass index(BMI),systolic blood,diastolic blood,parathormone(PTH),serum phosphorus level and residual renal function(RRF).Furthermore,the former group had more urine volume(24 hours),higher LVMI and the prevalence of LVH,while hemoglobin and serum albumin level were significantly lower(all P<0.05).Multivariate Logistic regression analysis showed that the progress on LVMI was positively correlated with the systolic pressure and serum phosphorus(OR=1.043,2.698,respectively,all P<0.05),and negatively correlated with the hemoglobin,serum albumin,RRF(OR=0.970,0.925,0.847,respectively,all P<0.05).Conclusion Systolic pressure,serum phosphorus,hemoglobin,serum albumin and RRF were influencing factors for the progress on LVMI.
作者
施秋泓
冯胜
高芦燕
沈华英
宋锴
Shi Qiuhong;Feng Sheng;GaoLuyan(Department of Nephrology,The Second Hospital Affiliated to Soochow University,Jiangsu 215000,China)
出处
《医学研究杂志》
2021年第5期108-111,共4页
Journal of Medical Research
基金
江苏省苏州市“科教兴卫”青年科技项目(KJXW2020017)。
关键词
腹膜透析
左心室质量指数
影响因素
Peritoneal dialysis
Left ventricular mass index
Influencing factors
