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参一胶囊对晚期肺鳞癌患者炎症反应及免疫功能的影响

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摘要 目的:研究参一胶囊辅助吉西他滨联合奈达铂化疗对晚期肺鳞癌患者血清、EBG中ET-1及T淋巴细胞亚群水平的影响。方法:选取我院2018年6月至2020年1月收治的晚期肺鳞癌患者80例,根据随机数字表法分为对照组和研究组,各40例。对照组采用吉西他滨联合奈达铂化疗,研究组在此基础上加用参一胶囊治疗,3周为1个疗程,两组均治疗4~6个疗程。比较两组患者治疗后临床疗效,治疗前后血清、EBG中ET-1和血清ALB及外周血CD4+百分比、CD8+百分比、CD4+/CD8+百分比水平。结果研究组临床总有效率55.00%,高于对照组35.00%;治疗后研究组患者外周血CD4+百分比、CD8+百分比、CD4+/CD8+百分比水平均高于对照组;治疗后两组患者血清、EBG中ET-1、血清ALB、外周血CD8+百分比水平均降低,且研究组低于对照组(P<0.05)。结论参一胶囊辅助吉西他滨联合奈达铂化疗治疗晚期肺鳞癌患者可有效缓解临床症状,降低机体炎症反应,改善免疫功能。
作者 王震
出处 《黑龙江中医药》 2021年第1期136-137,共2页 Heilongjiang Journal of Traditional Chinese Medicine
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  • 1梅少林,袁红艳,常雅萍,李平亚,卢丹.人参皂苷Rg3体外抗HSV-1活性与免疫调节效应[J].吉林大学学报(医学版),2006,32(6):1019-1022. 被引量:12
  • 2梅少林,袁红艳,曹湘博,常雅萍,李平亚,刘金萍.人参皂苷Rg3对HSE模型鼠的治疗作用及免疫调节效应[J].吉林大学学报(医学版),2007,33(1):119-122. 被引量:12
  • 3NATIONAL LUNG SCREENING TRIAL RESEARCH TEAM,ABERLE D R,ADAMS A M. Reduced lung-cancer mortality with low-dose computed tomographic screening[J].New England Journal of Medicine,2011,(05):395-409.
  • 4HENSCHKE C I,BOFFETTA P,GORLOVA O. Assessment of lung-cancer mortality reduction from CT screening[J].Lung Cancer,2011,(03):328-332.
  • 5JEMAL A,THUN M J,RIES L A. Annual report to the nation on the status of cancer,1975-2005,featuring trends in lung cancer,tobacco use,and tobacco control[J].JOURNAL OF THE NATIONAL CANCER INSTITUTE,2008,(23):1672-1694.
  • 6CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC). Smoking-attributable mortality,years of potential life lost,and productivity losses--United States,2000-2004[J].Morbidity and Mortality Weekly Report,2008,(45):1226-1228.
  • 7PETO R,DARBY S,DEO H. Smoking,smoking cessation,and lung cancer in the UK since 1950:combination of national statistics with two case-control studies[J].BMJ:British Medical Journal,2000,(7257):323-329.
  • 8GARFINKEL L. Time trends in lung cancer mortality among nonsmokers and a note on passive smoking[J].JOURNAL OF THE NATIONAL CANCER INSTITUTE,1981,(06):1061-1066.
  • 9DRISCOLL T,NELSON D I,STEENLAND K. The global burden of disease due to occupational carcinogens[J].AmJ Ind Med,2005,(06):419-431.
  • 10REID A,DE KLERK N H,AMBROSINI G L. The risk of lung cancer with increasing time since ceasing exposure to asbestos and quitting smoking[J].OCCUPATIONAL AND ENVIRONMENTAL MEDICINE,2006,(08):509-512.

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