摘要
长余辉纳米颗粒(PLNPs)因其独特而卓越的发光现象,可实现无损伤、无背景干扰的成像、检测及诊疗。PLNPs的发光中心决定其发射波长。以Cr^(3+)为发光中心的PLNPs由于发出近红外(NIR)光,组织穿透性良好,具有NIR光可激励的超强的持久余辉(PL)等优点,在生物医学研究中得到广泛应用。对Cr-PLNPs在生物检测、成像及多种治疗领域中的应用研究成果进行评述,分析了Cr-PLNPs研究领域存在的问题和挑战,指出了该领域的未来研究方向。
Persistent luminescence nanoparticles(PLNPs)can realize nondestructive imaging,detection,diagnosis and treatment without background interference due to their unique and outstanding luminescence phenomena.In addition,the emission wavelength of PLNPs is determined by their luminescence center.Thus,Cr^(3+)-doped PLNPs(Cr-PLNPs)have attracted much attention in the biomedical field due to their near-infrared(NIR)light emission,good tissue penetrability,and ultra-strong persistent luminescence(PL)excited by NIR light.In this paper,we discussed the application of Cr-PLNPs to biological detection,imaging,and therapy,analyzed their problems,and pointed out their future research directions.
作者
杨倩婷
热娜古丽·阿不都热合曼
燕音
姑丽各娜·买买提依明
Yang Qianting;Renagul Abdurahman;Yan Yin;Gulgina Mamtimin(Laboratory of Xinjiang Native Medicinal and Edible Plant Resources Chemistry,College of Chemistry and Environmental Science,Kashi University,Kashgar,Xinjiang 844000,China)
出处
《激光与光电子学进展》
CSCD
北大核心
2021年第8期31-44,共14页
Laser & Optoelectronics Progress
基金
国家自然科学基金(21867014)
新疆维吾尔自治区“天山青年”计划科技人才培养项目(2017Q086)
喀什大学高层次人才科研启动经费项目(GCC18ZK-003)
喀什大学博士专项项目((16)2579)。
