摘要
目的本文旨在研究呼气时间常数(RCEXP)在学龄期儿童常规通气肺功能测定中的应用价值。方法选择2018年8月至2020年8月在郑州大学第三附属医院、河南省漯河市第二人民医院和河南省洛阳市妇幼保健院行常规通气肺功能测定的442例学龄期儿童。分析不同性别、年龄和身高儿童RCEXP的差异性;肺功能正常组分别与不同气道阻塞组之间计算各组的RCEXP值,并做出相应的ROC曲线;探究RCEXP与肺功能参数之间的关联。结果女童RCEXP显著小于男童(P<0.001)、低年龄组RCEXP显著小于高年龄组(P<0.05),低身高组RCEXP显著小于高身高组(P<0.05);正常组RCEXP显著小于气道阻塞组(P<0.001),RCEXP的cutoff值为0.436;正常组RCEXP显著小于大气道阻塞组(P<0.001),RCEXP的cutoff值为0.575;正常组RCEXP显著小于小气道阻塞组(P<0.001),RCEXP的cutoff值为0.434。RCEXP与FEV1/FVC%呈负相关。结论学龄期儿童RCEXP延长提示气道阻塞;RCEXP大于0.436、0.575、0.434 s分别提示存在气道阻塞、大气道阻塞和小气道阻塞。
Objective To investigate the value of Expiratory time constant(RCEXP)in the measurement of routine ventilatory pulmonary function test of school⁃aged children.Methods A total of 442 school⁃aged children received routine pulmonary function measurements in the Third Affiliated Hospital of Zhengzhou University,Luohe Second People′s Hospital and Luoyang Maternal and Children Health Hospital between August 2018 and August 2020 were selected.RCEXP differences between sexes,ages,and heights were investigated,and RCEXP values were calculated between groups with normal lung function and groups with various airway obstructions.Furthermore,the corresponding ROC curves were created.The relationships between RCEXP and pulmonary function parameters were investigated.Results RCEXP of girls was significantly lower than that of boys(P<0.001),RCEXP of younger age group was significantly lower than that of older age group(P<0.05),and RCEXP of lower height group was signifi⁃cantly lower than that of higher height group(P<0.05);The RCEXP of girls was significantly lower than that of boys.The RCEXP of low age group was significantly lower than that of high age group and the RCEXP of low height group was significantly lower than that of high height group(P<0.05);RCEXP in the normal group was significant⁃ly lower than that in the airway obstruction group(P<0.001),and the cutoff value of RCEXP was 0.436.RCEXP in the normal group was significantly lower than that in the large airway obstruction group(P<0.001),and the cutoff value of RCEXP was 0.575.In addition,RCEXP in the normal group was significantly lower than that in the small airway obstruction group(P<0.001),and the cutoff value of RCEXP was 0.434;RCEXP was negatively correlated with FEV1/FVC%.Conclusion High RCEXP in school⁃aged children suggests airway obstruction.Airway obstruc⁃tion,large airway obstruction,and minor airway obstruction were indicated by RCEXP values greater than 0.436 s,0.575 s,and 0.434 s,respectively.
作者
张艳丽
王潇
苏爱芳
代富力
王秀芳
张艳
郑月红
蔡春玲
师红可
ZHANG Yanli;WANG Xiao;SU Aifang;DAI Fuli;WANG Xiufang;ZHANG Yan;ZHENG Yuehong;CAI Chunling;SHI Hongke(Department of Pediatrics,Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China;不详)
出处
《实用医学杂志》
CAS
北大核心
2021年第11期1428-1432,共5页
The Journal of Practical Medicine
基金
2019年度河南省医学科技攻关计划(联合共建)项目(编号:LHGJ20190342)。
关键词
RCEXP
学龄期儿童
肺功能
气道阻塞
应用价值
RCEXP
school⁃aged children
pulmonary function
airway obstruction
application value
