摘要
目的探讨0.01%阿托品滴眼液采用不同的给药方式对儿童及青少年的近视控制的影响。方法选取在本院青少年低视力防控中心就诊的近视儿童120例(240眼),采用随机数字表法分成三组:A组38例患者给予浓度为0.01%的阿托品滴眼液,点双眼,每晚一次,一次一滴;B组42例患者给予浓度为0.01%的阿托品滴眼液,点双眼,隔日一次,一次一滴;C组40例患者每晚给予浓度为0.1%的玻璃酸钠滴眼液,点双眼,每次一滴。比较三组等效球镜度数、眼轴及眼压,并记录治疗过程中的不良反应。结果三组治疗前后等效球镜度数及眼轴变化比较,差异有统计学意义(P<0.05);三组治疗前后眼压变化的比较,差异无统计学意义(P>0.05);三组治疗后均无明显不良反应。结论长期使用0.01%阿托品可以有效控制青少年的近视发展,且每日一次的给药方式对近视的控制作用最明显。
Objective To explore the effect of different ways of administering 0.01%atropine eye drops on the control of myopia in children and adolescents.Methods A total of 120 myopic patients(240 eyes)who were treated at the Youth Low Vision Prevention and Control Center of our hospital were selected and randomly divided into three groups.All patients were given atropine eye drops with a concentration of 0.01%,38 cases in group A were applied to both eyes,once every night,one drop at a time;42 patients in group B were applied to both eyes,once every other day,one drop at a time;40 patients in group C were applied to both eyes,one drop at a time.The equivalent spherical lens power,eye axis and intraocular pressure and adverse reactions were compared among the three groups.Results There were statistically significant difference in the changes of equivalent spherical lens power and eye axis among the three groups before and after treatment(P<0.05).the comparison of the changes in intraocular pressure before and after treatment among the three groups was not statistically significant(P>0.05).There were no obvious adverse reactions in the three groups after treatment.Conclusion Long-term use of 0.01%atropine can effectively control the development of myopia in children and adolescents,and the once-a-day administration method has the best effect.
作者
毕双双
马雪峰
戴馨
Bi Shuangshuang;MA Xuefeng;DAI Xin(Heze Medical College,Heze 274000,Shandong)
出处
《菏泽医学专科学校学报》
2021年第2期33-34,43,共3页
Journal of Heze Medical College
基金
菏泽医学专科学校校级科研课题(H17K08)。
关键词
阿托品
青少年
近视
Atropine
Adolescent
Myopia
